Evidence map›Paper›PMID 32765043›Full record

ArticlePharmacogenomics and personalized medicine2020

Development of Customizable Implementation Guides to Support Clinical Adoption of Pharmacogenomics: Experiences of the Implementing GeNomics In pracTicE (IGNITE) Network.

Benjamin Q Duong, Meghan J Arwood, J Kevin Hicks, Amber L Beitelshees, Francesco Franchi, John T Houder, Nita A Limdi, Kelsey J Cook, Aniwaa Owusu Obeng, Natasha Petry and 5 more

Abstract read
In one paragraph

Article in Pharmacogenomics and personalized medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. The Role of the Pediatric Pharmacist in Precision Medicine and Clinical Pharmacogenomics for Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Pharmaco-Multiomics: A New Frontier in Precision Psychiatry.International journal of molecular sciences · 2025
    Review
  7. Article
  8. Article
  9. Advancing Pharmacogenomics from Single-Gene to Preemptive Testing.Annual review of genomics and human genetics · 2022
    Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Resolving discordantPharmacogenomics · 2021
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Benjamin Q DuongDepartment of Precision Medicine, Nemours/Alfred I. DuPont Hospital for Children, Wilmington, DE, USA.ORCID 0000-0002-1814-5078
Meghan J ArwoodDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics & Precision Medicine, University of Florida College of Pharmacy, Gainesville, FL, USA.ORCID 0000-0003-3117-7450
J Kevin HicksDepartment of Individualized Cancer Management, Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0003-2314-0164
Amber L BeitelsheesDepartment of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.ORCID 0000-0003-0958-7197
Francesco FranchiDepartment of Cardiology, University of Florida College of Medicine, Jacksonville, FL, USA.
John T HouderDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics & Precision Medicine, University of Florida College of Pharmacy, Gainesville, FL, USA.ORCID 0000-0002-0219-3227
Nita A LimdiUniversity of Alabama School at Birmingham, Birmingham, AL, USA.
Kelsey J CookDepartment of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Jacksonville, FL, USA.
Aniwaa Owusu ObengThe Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Natasha PetryDepartment of Pharmacy Practice, North Dakota State University College of Health Professions, Fargo, ND, USA.ORCID 0000-0001-5089-9286
Sony TutejaPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-7007-3289
Amanda R ElseyDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics & Precision Medicine, University of Florida College of Pharmacy, Gainesville, FL, USA.
Larisa H CavallariDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics & Precision Medicine, University of Florida College of Pharmacy, Gainesville, FL, USA.
Kristin WiisanenDepartment of Pharmacotherapy and Translational Research and Center for Pharmacogenomics & Precision Medicine, University of Florida College of Pharmacy, Gainesville, FL, USA.ORCID 0000-0002-4946-7504
IGNITE Network

Funding

Impact of the gut microbiome on response to lipid lowering therapyK23HL143161 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI TUTEJA, SONY · 2019 to 2022
$695k
NHLBI NIH HHS K23 HL143161
6 · The paper itself

Abstract

introductionClinical adoption of genomic medicine has lagged behind the pace of scientific discovery. Practice-based resources can help overcome implementation challenges.

methodsIn 2015, the IGNITE (Implementing GeNomics In pracTicE) Network created an online genomic medicine implementation resource toolbox that was expanded in 2017 to incorporate the ability for users to create targeted implementation guides. This expansion was led by a multidisciplinary team that developed an evidence-based, structured framework for the guides, oversaw the technical process/build, and pilot tested the first guide,

resultsSixty-five resources were collected from 12 institutions and categorized according to a seven-step implementation framework for the pilot

conclusionLessons learned from this implementation guide development process provide insight for prioritizing development of future resources and support the value of collaborative efforts to create resources for genomic medicine implementation.

Indexed as

clinical pharmacogenomicsclopidogrelCYP2C19CYP2D6implementationpersonalized medicinepharmacogenomicsprecision medicine

Identifiers

PMID32765043
PMCPMC7373415

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.