Evidence map›Paper›PMID 32764879›Full record

ArticleDrug design, development and therapy2020

A Synthetic Peptide 2Abz

Neda Moazzezy, Mohammad Reza Asadi Karam, Sima Rafati, Saeid Bouzari, Mana Oloomi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug design, development and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Effects of pH on the Pathogenicity ofInternational journal of molecular sciences · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Neda MoazzezyMolecular Biology Department, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0002-3054-6800
Mohammad Reza Asadi KaramMolecular Biology Department, Pasteur Institute of Iran, Tehran, Iran.
Sima RafatiImmunotherapy and Leishmania Vaccine Research Department, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0002-7221-1320
Saeid BouzariMolecular Biology Department, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0002-3134-9665
Mana OloomiMolecular Biology Department, Pasteur Institute of Iran, Tehran, Iran.ORCID 0000-0002-4723-5021
Pasteur Institute of Iran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA urinary tract infection (UTI), which is often caused by uropathogenic

methodsThis study aimed to examine the antibacterial and immunomodulatory effects of different doses of truncated alpha-defensins (human neutrophil peptide (HNP)-1) analog 2Abz

resultsThe in vivo results showed that fewer UPEC were recovered from the bladders of mice treated transurethrally with 2Abz

conclusionCollectively, apart from the direct antibacterial role of 2Abz

Indexed as

Disease Models, AnimalAnimalsAnti-Bacterial AgentsCells, CulturedCytokinesFemaleHumansImmunologic FactorsMiceMice, Inbred BALB CPeptidesUrinary Tract InfectionsUropathogenic Escherichia coliAnti-Bacterial AgentsCytokinesImmunologic FactorsPeptideshuman neutrophil peptide (HNP)-1pro-inflammatory cytokinesurinary tract infection

Identifiers

PMID32764879
PMCPMC7381768
OpenAlexW3043065575

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.