Evidence map›Paper›PMID 32764852›Full record

ArticleJournal of obstetrics and gynaecology of India2020

Abdominal Tuberculosis Mimicking Ovarian Cancer: A Diagnostic Dilemma.

Anitha Thomas, Ajit Sebastian, Rachel George, Dhanya Susan Thomas, Grace Rebekah, Priscila Rupali, Joy Sarojini Michael, Abraham Peedicayil

Open access · greenAbstract read
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anitha ThomasDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu 632004 India.ORCID 0000-0002-5533-0184
Ajit SebastianDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Rachel GeorgeDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Dhanya Susan ThomasDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Grace RebekahDepartment of Biostatistics, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Priscila RupaliDepartment of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Joy Sarojini MichaelDepartment of Clinical Microbiology, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Abraham PeedicayilDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu 632004 India.
Christian Medical College, Vellore · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe objective of this study was to describe the clinicopathological details in patients referred to the Gynaecologic Oncology Department with possible ovarian or primary peritoneal cancer where the final diagnosis turned out to be abdominal tuberculosis. METHODOLOGY: Retrospective chart analysis of 23 cases diagnosed with abdominal tuberculosis who were admitted under the Division of Gynaecologic Oncology suspected to have disseminated peritoneal malignancy, during 2014-2017.

resultsThere were 23 patients who were referred to the Gynaecologic Oncology outpatient for evaluation of ascites, to rule out malignancy. The mean age of this patient group was 35 years (SD 14.5, range 14-65). The mean CA 125 was 333.5 [400.7 (9.09-1568)]. Ascitic fluid analysis confirmed TB in 26%; omental biopsy revealed TB in 69%, and operative diagnostic procedures (laparoscopy and laparotomy) were done in 15 of the 23 patients which had a positive pick up rate of 100% to confirm the diagnosis of TB. Culture of ascitic fluid/omental tissue and PCR yields were poor with a pick up rate of 33% and 6%.

conclusionsAbdominal TB is common in India and can mimic ovarian malignancy, and hence, high degree of suspicion needed. The isolation of AFB is the gold standard for diagnosis of pulmonary tuberculosis but has a low yield in abdominal TB. Ultrasound-guided procedure is reasonable as an initial procedure. As much time can be lost in working up these patients through multiple diagnostic algorithms using ascitic tap, USG biopsy and then an operative procedure, diagnostic laparoscopy could be considered early in the work up. It is a simple, time-saving and cost-effective way of establishing a diagnosis sooner with least complications.

Indexed as

Abdominal/peritoneal tuberculosisAscites differentialsMimics of ovarian cancer

Identifiers

PMID32764852
PMCPMC7381535
OpenAlexW3021339383

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.