Evidence map›Paper›PMID 32764701›Full record

ArticleScientific reports2020

Prognostic role of radiological peritoneal cancer index in malignant peritoneal mesothelioma: national cohort study.

Silja A S Salo, Eila Lantto, Eric Robinson, Marjukka Myllärniemi, Sanna Laaksonen, Jarmo A Salo, Tuomo Rantanen, Ilkka Ilonen

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  4. Review
  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Silja A S SaloDepartment of Surgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.
Eila LanttoClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Eric RobinsonIcahn School of Medicine at Mount Sinai, New York, NY, USA.
Marjukka MyllärniemiClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Sanna LaaksonenClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Jarmo A SaloClinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Tuomo Rantanen *Department of Surgery, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland. tuomo.rantanen@kuh.fi.
Ilkka Ilonen *Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland.
Helsinki University Hospital · FIUniversity of Eastern Finland · FIUniversity of Helsinki · FIIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant peritoneal mesothelioma (MPeM) is a rare cancer of the mesothelial cells of the peritoneum. Computed tomography (CT) is considered the standard for first-line imaging of MPeM, diagnosis and risk stratification remains challenging. Peritoneal cancer index (PCI), as assessed by CT, is utilized in the prognostic assessment of other malignant intra-abdominal conditions; however, there is limited data concerning the utility of PCI in the diagnosis and workup of MPeM. We studied a retrospective cohort of all patients diagnosed with MPeM from 2000 to 2012 in Finland. CT and magnetic resonance imaging (MRI) were reviewed and scored by an experienced and blinded, board-certified abdominal radiologist. Additional clinical data and outcomes were obtained from Finnish Cancer Registry (FCR), the Workers' Compensations Center (WCC), and Statistics Finland (SF). Abdominal CT or MRI was available for 53 of 90 patients. The median radiographic PCI was 25. PCI score was correlated with overall survival (p = 0.004, Exp(B) = 1.064, 95% CI 1.020-1.110). PCI score ≥ 30 was associated with worse survival (p = 0.002), while PCI ≤ 19 was associated with improved overall survival (p = 0.001). Our study indicates that radiological PCI is prognostic in MPeM and should be assessed during radiographic workup and integrated into clinical decision-making.

Indexed as

AgedClinical Decision-MakingCohort StudiesFemaleFinlandHumansMagnetic Resonance ImagingMalePeritoneal NeoplasmsPrognosisRadiographic Image Interpretation, Computer-AssistedRetrospective StudiesSurvival AnalysisTomography, X-Ray Computed

Identifiers

PMID32764701
PMCPMC7411064
OpenAlexW3047566251

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.