Evidence map›Paper›PMID 32764574›Full record

ArticleScientific reports2020

D2 dopamine receptor gene (DRD2) Taq1A (rs1800497) affects bone density.

Ting-I Chiang, Hsien-Yuan Lane, Chieh-Hsin Lin

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Novel SNP Combination for Predictive Osteoporotic Diagnosis.International journal of molecular sciences · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Dopamine, Immunity, and Disease.Pharmacological reviews · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ting-I ChiangDepartment of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong District, Kaohsiung City, 833, Taiwan.ORCID http://orcid.org/0000-0001-7548-0967
Hsien-Yuan LaneGraduate Institute of Biomedical Sciences, China Medical University, No. 91, Hsueh-Shih Rd., North Dist., Taichung City, 404, Taiwan. hylane@gmail.com.
Chieh-Hsin LinDepartment of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, No. 123, Dapi Rd., Niaosong District, Kaohsiung City, 833, Taiwan. cyndi36@gmail.com.
Chang Gung University · TWAsia University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia patients are susceptible to lower bone mineral density (BMD). However, studies exploring the genetic effects are lacking. Genes that affect the activity of antipsychotics may be associated with BMD, particularly in patients receiving long-term antipsychotic treatment. We aimed to explore the relationship between the dopamine receptor D

Indexed as

Polymorphism, Single NucleotideAbsorptiometry, PhotonBone DensityCase-Control StudiesFemaleGenetic Predisposition to DiseaseHumansMaleReceptors, Dopamine D2SchizophreniaTaiwanDRD2 protein, humanReceptors, Dopamine D2

Identifiers

PMID32764574
PMCPMC7414035
OpenAlexW3047383021

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.