Evidence map›Paper›PMID 32764497›Full record

ArticleGenes2020

DNA6mA-MINT: DNA-6mA Modification Identification Neural Tool.

Mobeen Ur Rehman, Kil To Chong

Abstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
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  5. 4acCPred: Weakly supervised prediction ofMolecular therapy. Nucleic acids · 2022
    Article
  6. Article
  7. Identification of piRNA disease associations using deep learning.Computational and structural biotechnology journal · 2022
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mobeen Ur RehmanDepartment of Electronics and Information Engineering, Jeonbuk National University, Jeonju 54896, Korea.
Kil To ChongDepartment of Electronics and Information Engineering, Jeonbuk National University, Jeonju 54896, Korea.ORCID 0000-0002-1952-0001

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DNA N6-methyladenine (6mA) is part of numerous biological processes including DNA repair, DNA replication, and DNA transcription. The 6mA modification sites hold a great impact when their biological function is under consideration. Research in biochemical experiments for this purpose is carried out and they have demonstrated good results. However, they proved not to be a practical solution when accessed under cost and time parameters. This led researchers to develop computational models to fulfill the requirement of modification identification. In consensus, we have developed a computational model recommended by Chou's 5-steps rule. The Neural Network (NN) model uses convolution layers to extract the high-level features from the encoded binary sequence. These extracted features were given an optimal interpretation by using a Long Short-Term Memory (LSTM) layer. The proposed architecture showed higher performance compared to state-of-the-art techniques. The proposed model is evaluated on

Indexed as

DNA MethylationSoftwareAdenineAnimalsDeep LearningEpigenomicsMiceOryza6-methyladenineAdenineChou’s 5-steps rulecomputational biologyConvolution Neural Network (CNN)DNA N6-methyladenineLong Short-Term Memory (LSTM)

Identifiers

PMID32764497
PMCPMC7463462

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.