Evidence map›Paper›PMID 32764415›Full record

ArticleGenes2020

The Impact of Coilin Nonsynonymous SNP Variants E121K and V145I on Cell Growth and Cajal Body Formation: The First Characterization.

Yue Yao, Heng Wee Tan, Zhan-Ling Liang, Gao-Qi Wu, Yan-Ming Xu, Andy T Y Lau

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. A Novel Role for Coilin in Vertebrate Innate Immunity.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yue YaoLaboratory of Cancer Biology and Epigenetics, Shantou University Medical College, Shantou 515041, Guangdong, China.ORCID 0000-0002-9333-1559
Heng Wee TanLaboratory of Cancer Biology and Epigenetics, Shantou University Medical College, Shantou 515041, Guangdong, China.ORCID 0000-0001-5795-2449
Zhan-Ling LiangLaboratory of Cancer Biology and Epigenetics, Shantou University Medical College, Shantou 515041, Guangdong, China.ORCID 0000-0002-9533-020X
Gao-Qi WuLaboratory of Cancer Biology and Epigenetics, Shantou University Medical College, Shantou 515041, Guangdong, China.ORCID 0000-0002-9771-7213
Yan-Ming XuDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou 515041, Guangdong, China.ORCID 0000-0003-1124-0045
Andy T Y LauLaboratory of Cancer Biology and Epigenetics, Shantou University Medical College, Shantou 515041, Guangdong, China.ORCID 0000-0002-7146-7789
Shantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coilin is the main component of Cajal body (CB), a membraneless organelle that is involved in the biogenesis of ribonucleoproteins and telomerase, cell cycle, and cell growth. The disruption of CBs is linked to neurodegenerative diseases and potentially cancers. The coilin gene (

Indexed as

Cell ProliferationPolymorphism, Single NucleotideCoiled BodiesHeLa CellsHumansMutation, MissenseNuclear ProteinsProtein DomainsProtein StabilityProtein TransportNuclear Proteinsp80-coilincancer riskCOILmutationsingle nucleotide polymorphismSMN

Identifiers

PMID32764415
PMCPMC7463897
OpenAlexW3047153423

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.