ReviewAntioxidants (Basel, Switzerland)2020
The Versatility of Antioxidant Assays in Food Science and Safety-Chemistry, Applications, Strengths, and Limitations.
Review in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 233 papers.
What it found
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Who cites it
233 citing papers in PubMed, 550 citations in OpenAlex.
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- Powdered Herbal Extracts by Freeze and Spray Drying: Formulation Design, Processing, and Physicochemical and Antiglycation Properties.Foods (Basel, Switzerland) · 2026Article
- Integrated Sugar-Acid-Phenolic Profiling Identifies Distinct Chemical Types Associated with Antioxidant Capacity in Apple Pulp Samples.Foods (Basel, Switzerland) · 2026Article
- In Vitro Antioxidant Activity and Dual-Target Inhibitory Effects of Dipyridamole on α-Amylase and α-Glucosidase: Molecular Mechanisms and Molecular Dynamics Simulations.Biomolecules · 2026Article
- Article
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- Optimized Extraction and Bioactivity Profiling of Phenolics from Bostrychia scorpioides (Hudson) Mont: A Sustainable Approach for Pharmaceuticals Applications.Marine biotechnology (New York, N.Y.) · 2026Article
- Solvent-Dependent Phytochemical Profiles, Antioxidant and Antimicrobial Bioactivities, and Melanoma-Selective Cytotoxicity ofMolecules (Basel, Switzerland) · 2026Article
- Synthesis and Biological Evaluation of Thiophene-Bridged Indole-Artesunate Hybrids as Selective Anticancer Agents.ACS omega · 2026Article
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- Optimized Ultrasound-Assisted Extraction Enhances the Recovery of Anti-Collagenase Phytochemicals fromPlants (Basel, Switzerland) · 2026Article
- Online HPLC-Guided Screening of Chemical Composition and Bioactivity in Capparis ovata subsp. canescens.Chemistry & biodiversity · 2026Article
- Potent Therapeutic Insights FromFood science & nutrition · 2026Article
- Phytochemical Characterization ofFood science & nutrition · 2026Article
- Enzyme Co-Immobilization on Precipitated Silica for Sustainable Lactobionic Acid Production.Molecules (Basel, Switzerland) · 2026Article
- Unlocking Antioxidant Potential in Wheat By-Products Through Microbial Bioprocessing: An Integrated Extraction-QUENCHER Assessment.Molecules (Basel, Switzerland) · 2026Article
- Comparative Phytochemical Profiling and Cellular Antioxidant and Anti-Inflammatory Effects of Wild and CultivatedAntioxidants (Basel, Switzerland) · 2026Article
- Integrated Assessment of Bioactive Properties of NinePlants (Basel, Switzerland) · 2026Article
173 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Currently, there is a growing interest in screening and quantifying antioxidants from biological samples in the quest for natural and effective antioxidants to combat free radical-related pathological complications. Antioxidant assays play a crucial role in high-throughput and cost-effective assessment of antioxidant capacities of natural products such as medicinal plants and food samples. However, several investigators have expressed concerns about the reliability of existing in vitro assays. Such concerns arise mainly from the poor correlation between in vitro and in vivo results. In addition, in vitro assays have the problem of reproducibility. To date, antioxidant capacities are measured using a panel of assays whereby each assay has its own advantages and limitations. This unparalleled review hotly disputes on in vitro antioxidant assays and elaborates on the chemistry behind each assay with the aim to point out respective principles/concepts. The following critical questions are also addressed: (1) What make antioxidant assays coloured? (2) What is the reason for working at a particular wavelength? (3) What are the advantages and limitations of each assay? and (4) Why is a particular colour observed in antioxidant-oxidant chemical reactions? Furthermore, this review details the chemical mechanism of reactions that occur in each assay together with a colour ribbon to illustrate changes in colour. The review ends with a critical conclusion on existing assays and suggests constructive improvements on how to develop an adequate and universal antioxidant assay.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.