Evidence map›Paper›PMID 32764360›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Immunological and Microbiological Profiling of Cumulative Risk Score for Periodontitis.

Joonas Liukkonen, Ulvi K Gürsoy, Eija Könönen, Ramin Akhi, Aino Salminen, John M Liljestrand, Pratikshya Pradhan-Palikhe, Milla Pietiäinen, Timo Sorsa, G Rutger Persson and 6 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. A REVIEW OF SALIVARY BIOMARKERS OF PERIODONTAL DISEASE.Annals of Ibadan postgraduate medicine · 2024
    Article
  4. Total fecal IgA levels increase and natural IgM antibodies decrease after gastric bypass surgery.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2022
    Article
  5. Review
  6. Review
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 4 countries.

Joonas LiukkonenInstitute of Dentistry, University of Turku, 20100 Turku, Finland.ORCID 0000-0003-3948-3479
Ulvi K GürsoyInstitute of Dentistry, University of Turku, 20100 Turku, Finland.ORCID 0000-0002-1225-5751
Eija KönönenInstitute of Dentistry, University of Turku, 20100 Turku, Finland.
Ramin AkhiMedical Microbiology and Immunology, Research Unit of Biomedicine, University of Oulu, 90100 Oulu, Finland.ORCID 0000-0003-1783-5330
Aino SalminenOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.
John M LiljestrandOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.
Pratikshya Pradhan-PalikheOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.
Milla PietiäinenOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.ORCID 0000-0002-4875-0682
Timo SorsaOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.
G Rutger PerssonDepartments of Periodontics and Oral Medicine, University of Washington, Seattle, WA 98101, USA.
Päivi MäntyläOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.ORCID 0000-0003-2091-972X
Kåre BuhlinOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.
Susanna PajuOral and Maxillofacial diseases, University of Helsinki and Helsinki University Hospital, 00100 Helsinki, Finland.ORCID 0000-0002-2048-3420
Juha SinisaloHUCH Heart and Lung Center, Helsinki University Central Hospital, 00100 Helsinki, Finland.
Sohvi HörkköMedical Microbiology and Immunology, Research Unit of Biomedicine, University of Oulu, 90100 Oulu, Finland.
Pirkko J PussinenInstitute of Dentistry, University of Turku, 20100 Turku, Finland.ORCID 0000-0003-3563-1876
University of Helsinki · FIUniversity of Turku · FIOulu University Hospital · FIHelsinki University Hospital · FIUniversity of Bern · CH

Funding

Academy of Finland 1266053Helsingin ja Uudenmaan Sairaanhoitopiiri TYH2012005Helsingin ja Uudenmaan Sairaanhoitopiiri TYH2012209
6 · The paper itself

Abstract

The cumulative risk score (CRS) is a mathematical salivary diagnostic model to define an individual's risk of having periodontitis. In order to further validate this salivary biomarker, we investigated how periodontal bacteria, lipopolysaccharide (LPS), and systemic and local host immune responses relate to CRS. Subgingival plaque, saliva, and serum samples collected from 445 individuals were used in the analyses. Plaque levels of 28 microbial species, especially those of

Indexed as

bacteriabiomarkerslipopolysaccharidessalivaserum

Identifiers

PMID32764360
PMCPMC7460115
OpenAlexW3047104665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.