Evidence map›Paper›PMID 32764353›Full record

ArticleInternational journal of molecular sciences2020

Synthesis and Pharmacological Characterization of 2-Aminoethyl Diphenylborinate (2-APB) Derivatives for Inhibition of Store-Operated Calcium Entry (SOCE) in MDA-MB-231 Breast Cancer Cells.

Achille Schild, Rajesh Bhardwaj, Nicolas Wenger, Dominic Tscherrig, Palanivel Kandasamy, Jan Dernič, Roland Baur, Christine Peinelt, Matthias A Hediger, Martin Lochner

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Developing Optogenetic Approaches to Study CaCold Spring Harbor perspectives in biology · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Blockade of store-operated calcium entry sensitizes breast cancer cells to cisplatin therapy via modulating inflammatory response.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  8. Review
  9. Article
  10. Calcium Signalling in Breast Cancer Associated Bone Pain.International journal of molecular sciences · 2022
    Review
  11. TRPC6, a therapeutic target for pulmonary hypertension.American journal of physiology. Lung cellular and molecular physiology · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Therapeutic effects of SKF-96365 on murine allergic rhinitis induced by OVA.International journal of immunopathology and pharmacology
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Achille SchildInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.ORCID 0000-0002-7987-8013
Rajesh BhardwajDepartment of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.ORCID 0000-0002-5599-487X
Nicolas WengerDepartment of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Dominic TscherrigInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Palanivel KandasamyDepartment of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.ORCID 0000-0003-3795-2876
Jan DerničDepartment of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Roland BaurInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.
Christine PeineltInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.ORCID 0000-0002-3474-6893
Matthias A HedigerDepartment of BioMedical Research, University of Bern, Murtenstrasse 35, 3008 Bern, Switzerland.
Martin LochnerInstitute of Biochemistry and Molecular Medicine, University of Bern, Bühlstrasse 28, 3012 Bern, Switzerland.ORCID 0000-0003-4930-1886
University of Bern · CH

Funding

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung CRSII3_160782Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung CRSII5_180326
6 · The paper itself

Abstract

Calcium ions regulate a wide array of physiological functions including cell differentiation, proliferation, muscle contraction, neurotransmission, and fertilization. The endoplasmic reticulum (ER) is the major intracellular Ca

Indexed as

AnimalsBoron CompoundsBreast NeoplasmsCalciumCalcium SignalingEndoplasmic ReticulumFemaleGene Expression Regulation, NeoplasticHumansMultiprotein ComplexesNeoplasm ProteinsORAI1 ProteinSarcoplasmic Reticulum Calcium-Transporting ATPasesStromal Interaction Molecule 1Stromal Interaction Molecules2-aminoethyl diphenylborinateBoron CompoundsCalciumMultiprotein ComplexesNeoplasm ProteinsORAI1 ProteinSarcoplasmic Reticulum Calcium-Transporting ATPasesSTIM1 protein, humanStromal Interaction Molecule 1Stromal Interaction Molecules2-APBbreast cancer cellscalcium imaging assayinhibitorspatch-clamp electrophysiologystore-operated calcium entrystructure–activity relationshipsynthetic chemistry

Identifiers

PMID32764353
PMCPMC7460636
OpenAlexW3047400476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.