Evidence map›Paper›PMID 32764328›Full record

ArticleJournal of clinical medicine2020

Exhaled Biomarkers in Idiopathic Pulmonary Fibrosis-A Six-Month Follow-Up Study in Patients Treated with Pirfenidone.

Kaja Jaskiewicz, Katarzyna Mycroft, Marta Maskey-Warzechowska, Karolina Paralusz, Natalia Siemiez, Patrycja Nejman-Gryz, Malgorzata Barnas, Rafal Krenke, Katarzyna Gorska

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kaja JaskiewiczDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-091 Warszawa, Poland.
Katarzyna MycroftDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-091 Warszawa, Poland.
Marta Maskey-WarzechowskaDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-091 Warszawa, Poland.
Karolina ParaluszStudents' Research Group "Alveolus", Medical University of Warsaw, 02-091 Warsaw, Poland.
Natalia SiemiezStudents' Research Group "Alveolus", Medical University of Warsaw, 02-091 Warsaw, Poland.
Patrycja Nejman-GryzDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-091 Warszawa, Poland.
Malgorzata BarnasDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-091 Warszawa, Poland.
Rafal KrenkeDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-091 Warszawa, Poland.
Katarzyna GorskaDepartment of Internal Medicine, Pulmonary Diseases and Allergy, Medical University of Warsaw, 02-091 Warszawa, Poland.
Medical University of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechanism of action of pirfenidone in idiopathic pulmonary fibrosis (IPF) has not been fully elucidated. To offer additional insight, we evaluated the change in the cytokine profile in exhaled breath condensate (EBC) following a six-month treatment with pirfenidone in patients with IPF. EBC concentrations of interleukin (IL)-6, IL-8, IL-15, TNF-α and VEGF-A were assessed with ELISA and compared at baseline and after six months of pirfenidone treatment. Twenty-nine patients with IPF and 13 controls were evaluated at baseline. With the exception of IL-8 concentration, which was lower in patients with IPF when compared to controls (

Indexed as

antifibrotic treatmentexhaled breath condensateinterleukinpulmonary fibrosisvascular endothelial growth factor

Identifiers

PMID32764328
PMCPMC7465603
OpenAlexW3047429705

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.