Evidence map›Paper›PMID 32764305›Full record

ReviewDentistry journal2020

Photobiomodulation and Oral Mucositis: A Systematic Review.

Mark Cronshaw, Steven Parker, Eugenia Anagnostaki, Valina Mylona, Edward Lynch, Martin Grootveld

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Dentistry journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 5 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 5 syntheses or guidelines pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. The supportive use of photobiomodulation on salivary glands: a narrative review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Mark CronshawLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
Steven ParkerLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.ORCID 0000-0003-2317-8381
Eugenia AnagnostakiLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.ORCID 0000-0003-2835-695X
Valina MylonaLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.ORCID 0000-0002-5212-5708
Edward LynchLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
Martin GrootveldLeicester School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.ORCID 0000-0003-1502-3734
De Montfort University · GBUniversity of Nevada, Las Vegas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral mucositis (OM) is a debilitating complication of chemotherapy, and head and neck radiotherapy. In an effort to offer the best possible advice within the limitations of published research, a systematic review with an extended discussion and commentary on dosimetry and dose delivery is presented. Using keywords as listed, Pubmed, Google Scholar and Cochrane databases were searched during a period extending from 1995 to 2019. A total of 782 abstracts were identified. A total of 50 papers were analysed, and of these, 29 satisfied criteria required for systematic review in accordance with an optimized PRISMA statement. Clinical outcome as reported was subject to analysis with respect to time of intervention, incidence and severity of oral mucositis, and pain amelioration, and a comprehensive combined univariate and multivariate statistical analysis of the methods employed was performed. Recommendations are made with respect to the timing of the intervention. Moreover, there is an extended discussion available on the treatment care rationale of photobiomodulation (PBM), and its adjunctive association with OM. In conclusion, early prophylactic application offers clear advantages in clinical management. The many studies and associated variables and covariables assessed here revealed a choice of delivery techniques, associated wavelengths and many further indices to consider with regard to the accomplishment of optical parameters. It is therefore our recommendation that clinicians use PBM as a therapy with a full and proper understanding and training in order to optimise the clinical effects achievable.

Indexed as

cancerchemotherapylaserLEDLLLTlow-level laser therapyoral mucositisphotobiomodulationradiotherapystomatitis

Identifiers

PMID32764305
PMCPMC7559189
OpenAlexW3047330204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.