Evidence map›Paper›PMID 32764303›Full record

ArticleMarine drugs2020

Transcriptomic Analysis of Four Cerianthid (Cnidaria, Ceriantharia) Venoms.

Anna M L Klompen, Jason Macrander, Adam M Reitzel, Sérgio N Stampar

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
10.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
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  9. Cnidarian toxins: omics approaches and recombinant proteins.The journal of venomous animals and toxins including tropical diseases · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Anna M L KlompenDepartment of Ecology and Evolutionary Biology, University of Kansas, 1200 Sunnyside Ave., Lawrence, KS 66045, USA.ORCID 0000-0001-8939-0057
Jason MacranderDepartment of Biological Sciences, University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte, NC 28262, USA.ORCID 0000-0002-1509-4332
Adam M ReitzelDepartment of Biological Sciences, University of North Carolina at Charlotte, 9201 University City Blvd, Charlotte, NC 28262, USA.ORCID 0000-0001-5734-7118
Sérgio N StamparDepartment of Biological Sciences, Universidade Estadual Paulista "Júlio de Mesquita Filho" (UNESP), FCL, Assis, SP 19806, Brazil.
University of North Carolina at Charlotte · USUniversidade Estadual Paulista (Unesp) · BRUniversity of Kansas · US

Funding

São Paulo Research Foundation FAPESP, SPRINT, CNPq(PROTAX), CNPq (Research Productivity Scholarship) 2015/24408-4, 2017/50028-0, 2019/03552-0, 440539/2015-3, 301293/2019-8
6 · The paper itself

Abstract

Tube anemones, or cerianthids, are a phylogenetically informative group of cnidarians with complex life histories, including a pelagic larval stage and tube-dwelling adult stage, both known to utilize venom in stinging-cell rich tentacles. Cnidarians are an entirely venomous group that utilize their proteinaceous-dominated toxins to capture prey and defend against predators, in addition to several other ecological functions, including intraspecific interactions. At present there are no studies describing the venom for any species within cerianthids. Given their unique development, ecology, and distinct phylogenetic-placement within Cnidaria, our objective is to evaluate the venom-like gene diversity of four species of cerianthids from newly collected transcriptomic data. We identified 525 venom-like genes between all four species. The venom-gene profile for each species was dominated by enzymatic protein and peptide families, which is consistent with previous findings in other cnidarian venoms. However, we found few toxins that are typical of sea anemones and corals, and furthermore, three of the four species express toxin-like genes closely related to potent pore-forming toxins in box jellyfish. Our study is the first to provide a survey of the putative venom composition of cerianthids and contributes to our general understanding of the diversity of cnidarian toxins.

Indexed as

Gene Expression ProfilingTranscriptomeAnimalsCnidariaCnidarian VenomsGene Expression RegulationPhylogenySpecies SpecificityCnidarian VenomsAnthozoaCeriantheomorphe brasiliensisIsarachnanthus nocturnusPachycerianthus borealisPachycerianthus cf. mauatoxinstranscriptometube anemonevenom-like

Identifiers

PMID32764303
PMCPMC7460484
OpenAlexW3047085282

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.