Evidence map›Paper›PMID 32764269›Full record

ReviewPharmaceutics2020

Skin Wound Healing Process and New Emerging Technologies for Skin Wound Care and Regeneration.

Erika Maria Tottoli, Rossella Dorati, Ida Genta, Enrica Chiesa, Silvia Pisani, Bice Conti

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 474 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
474citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

474 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
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  6. Trial
  7. Trial
  8. Article
  9. Article
  10. Review
  11. Article
  12. A CD14-Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  13. Callus Induction inPlants (Basel, Switzerland) · 2026
    Article
  14. Review
  15. Article
  16. Fish Collagen Hydrolysates in Wound Healing: A Patent Review.ACS pharmacology & translational science · 2026
    Review
  17. Review
  18. Article
  19. Article
  20. Article

414 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erika Maria TottoliDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.
Rossella DoratiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5774-9547
Ida GentaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0001-5710-0588
Enrica ChiesaDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.
Silvia PisaniImmunology and Transplantation Laboratory, Pediatric Hematology Oncology Unit, Department of Maternal and Children's Health, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.
Bice ContiDepartment of Drug Sciences, University of Pavia, V.le Taramelli 12, 27100 Pavia, Italy.ORCID 0000-0002-0034-2815

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Skin wound healing shows an extraordinary cellular function mechanism, unique in nature and involving the interaction of several cells, growth factors and cytokines. Physiological wound healing restores tissue integrity, but in many cases the process is limited to wound repair. Ongoing studies aim to obtain more effective wound therapies with the intention of reducing inpatient costs, providing long-term relief and effective scar healing. The main goal of this comprehensive review is to focus on the progress in wound medication and how it has evolved over the years. The main complications related to the healing process and the clinical management of chronic wounds are described in the review. Moreover, advanced treatment strategies for skin regeneration and experimental techniques for cellular engineering and skin tissue engineering are addressed. Emerging skin regeneration techniques involving scaffolds activated with growth factors, bioactive molecules and genetically modified cells are exploited to overcome wound healing technology limitations and to implement personalized therapy design.

Indexed as

3D bioprintingchronic woundsdrug deliveryelectrospinningwoundwound healing

Identifiers

PMID32764269
PMCPMC7463929

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.