Evidence map›Paper›PMID 32764239›Full record

ArticleAnimals : an open access journal from MDPI2020

Effects of Iron Deficiency on Serum Metabolome, Hepatic Histology, and Function in Neonatal Piglets.

Zhenglin Dong, Dan Wan, Huansheng Yang, Guanya Li, Yiming Zhang, Xihong Zhou, Xin Wu, Yulong Yin

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Zhenglin DongHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan international joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Dan WanKey Laboratory of Agro-Ecological Processess in Subtropical Region, Hunan Research Center of Livestock & Poultry Sciences, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, Hunan, China.
Huansheng YangHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan international joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Guanya LiHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan international joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Yiming ZhangHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan international joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Xihong ZhouKey Laboratory of Agro-Ecological Processess in Subtropical Region, Hunan Research Center of Livestock & Poultry Sciences, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, Hunan, China.ORCID 0000-0002-0007-3504
Xin WuKey Laboratory of Agro-Ecological Processess in Subtropical Region, Hunan Research Center of Livestock & Poultry Sciences, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, Hunan, China.
Yulong YinHunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan international joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University, Changsha 410081, Hunan, China.
Hunan Normal University · CNInstitute of Subtropical Agriculture · CN

Funding

the Hunan Province Key Laboratory of Animal Nutritional Physiology and Metabolic Process 2018TP1031the National Key R&D Program of China 2016YFD0501201the National Natural Science Foundation of China 31702127The Science and Technology Service Network Initiative program of Chinese Academy of Sciences KFJ-STS-QYZD-095the Young Elite Scientists Sponsorship Program by CAST 2018QNRC001
6 · The paper itself

Abstract

Few studies focused on the effects of iron on characterizing alterations of metabolic processes in neonatal piglets. In the present study, 16 neonatal piglets were randomly assigned to two groups. In the first group piglets were given an intramuscularly injection of iron dextran at 150 mg as a positive control (CON) and the second group were not supplemented with iron as a negative control for iron deficiency (ID). At day 8, iron status, serum biochemical parameters, serum metabolome, hepatic histology, and hepatic expression of genes for the metabolism were analyzed. Results indicated that piglets without iron supplementation had significantly reduced iron values and increased blood urea nitrogen concentrations at day 8 (

Indexed as

ironiron deficiencymetabolite signaturesmetabolomicsneonatal piglets

Identifiers

PMID32764239
PMCPMC7460156
OpenAlexW3047370356

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.