Evidence map›Paper›PMID 32764225›Full record

ArticleGenes2020

Increased Accumulation of Medium-Chain Fatty Acids by Dynamic Degradation of Long-Chain Fatty Acids in

Syed Ammar Hussain, Alexis Garcia, Md Ahsanul Kabir Khan, Shaista Nosheen, Yao Zhang, Mattheos A G Koffas, Victoriano Garre, Soo Chan Lee, Yuanda Song

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Mass spore production of3 Biotech · 2021
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 3 countries.

Syed Ammar HussainColin Ratledge Center for Microbial Lipids, School of Agriculture Engineering and Food Science, Shandong University of Technology, Zibo 255049, China.ORCID 0000-0003-0940-5939
Alexis GarciaDepartment of Biology, South Texas Center of Emerging Infectious Diseases (STCEID), University of Texas, San Antonio, TX 78249, USA.
Md Ahsanul Kabir KhanColin Ratledge Center for Microbial Lipids, School of Agriculture Engineering and Food Science, Shandong University of Technology, Zibo 255049, China.
Shaista NosheenColin Ratledge Center for Microbial Lipids, School of Agriculture Engineering and Food Science, Shandong University of Technology, Zibo 255049, China.ORCID 0000-0002-4098-1726
Yao ZhangColin Ratledge Center for Microbial Lipids, School of Agriculture Engineering and Food Science, Shandong University of Technology, Zibo 255049, China.
Mattheos A G KoffasDepartment of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.ORCID 0000-0002-1405-0565
Victoriano GarreDepartamento de Genética y Microbiología (Unidadasociada al IQFR-CSIC), Facultad de Biología, Universidad de Murcia, 30071 Murcia, Spain.ORCID 0000-0001-7605-1726
Soo Chan LeeDepartment of Biology, South Texas Center of Emerging Infectious Diseases (STCEID), University of Texas, San Antonio, TX 78249, USA.
Yuanda SongColin Ratledge Center for Microbial Lipids, School of Agriculture Engineering and Food Science, Shandong University of Technology, Zibo 255049, China.
Shandong University of Technology · CNTexas Center for Infectious Disease · USRensselaer Polytechnic Institute · USUniversidad de Murcia · ES

Funding

UTSA RISE Research Training ProgramR25GM060655 · NIGMS · UNIVERSITY OF TEXAS SAN ANTONIO · PI BAREA-RODRIGUEZ, EDWIN J · 2000 to 2022
$21.6M
National Institute of Allergy and Infectious Diseases R03 AI11917NIGMS NIH HHS R25 GM060655
6 · The paper itself

Abstract

Concerns about global warming, fossil-fuel depletion, food security, and human health have promoted metabolic engineers to develop tools/strategies to overproduce microbial functional oils directly from renewable resources. Medium-chain fatty acids (MCFAs, C8-C12) have been shown to be important sources due to their diverse biotechnological importance, providing benefits ranging from functional lipids to uses in bio-fuel production. However, oleaginous microbes do not carry native pathways for the production of MCFAs, and therefore, diverse approaches have been adapted to compensate for the requirements of industrial demand.

Indexed as

Acyl-CoA OxidaseFatty AcidsFatty Acid SynthasesFungal ProteinsIndustrial MicrobiologyMetabolic EngineeringMucorThiolester HydrolasesAcyl-CoA OxidaseFatty AcidsFatty Acid SynthasesFungal Proteinsoleoyl-(acyl-carrier-protein) hydrolaseThiolester Hydrolasesacyl-ACP-Thioesteraseacyl-CoA-oxidaseacyl-CoA-thioesterasefunctional lipidsgreen biofuelsmetabolic engineeringMucor circinelloidesβ-oxidation pathway

Identifiers

PMID32764225
PMCPMC7464202
OpenAlexW3046988870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.