Evidence map›Paper›PMID 32764146›Full record

ReviewProceedings of the National Academy of Sciences of the United States of America2020

PIP

Osama F Harraz, David Hill-Eubanks, Mark T Nelson

Open access · bronzeAbstract readReview
In one paragraph

Review in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 72 citations in OpenAlex.

  1. Review
  2. Article
  3. PIP4K attenuates PIP5K lipid kinase activity by disrupting membrane-mediated dimerization.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Review
  5. Article
  6. Cerebral capillary computation.American journal of physiology. Cell physiology · 2026
    Review
  7. Article
  8. Article
  9. Lipid Regulation of Mechanosensitive Ion Channels.International journal of molecular sciences · 2026
    Review
  10. Review
  11. Review
  12. Review
  13. PIPProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Article
  16. MAPK signaling and angiopoietin-2 contribute to endothelial permeability in capillary malformations.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  17. Article
  18. Article
  19. Review
  20. Lipid probes to study ion channels.Current opinion in chemical biology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Osama F HarrazDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, VT 05405.ORCID 0000-0003-2061-1100
David Hill-EubanksDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, VT 05405.
Mark T NelsonDepartment of Pharmacology, Larner College of Medicine, University of Vermont, Burlington, VT 05405; mark.nelson@uvm.edu.
University of Vermont · US

Funding

Impact of SAH on Parenchymal Arterioles and Neurovascular CouplingP01HL095488 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BONEV, ADRIAN · 2010 to 2014
$11.4M
Capillaries as a Sensory Web that Controls Cerebral Blood Flow in Health and DiseaseR35HL140027 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2019 to 2025
$6.3M
TRP Channel-Dependent Regulation of Arterial Tone (Renewal)R01HL091905 · NHLBI · UNIVERSITY OF NEVADA RENO · PI EARLEY, SCOTT · 2009 to 2020
$5.1M
Capillary control of cerebral blood flow, and its disruption in small vessel diseaseR01HL136636 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI Fabrice Dabertrand · 2017 to 2026
$3.8M
Ca2+ Sparks and Urinary Bladder Smooth Muscle ExcitabilityR37DK053832 · NIDDK · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2008 to 2017
$3.4M
Ion Channel Dysfunction in Small Vessel Disease of the BrainR01NS110656 · NINDS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2019 to 2023
$2.6M
Regulations of Myoendothelial Function By Signaling Microdomains in HypertensionR01HL121706 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2014 to 2017
$1.6M
K+ sensing & electrical signaling by Kir channels in brain vasculatureR01HL131181 · NHLBI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI NELSON, MARK T · 2016 to 2018
$1.4M
American Heart Association-American Stroke Association 17POST33650030American Heart Association-American Stroke Association 20CDA35310097 - OSAMA HARRAZNHLBI NIH HHS P01 HL095488NHLBI NIH HHS R01 HL091905NHLBI NIH HHS R01 HL121706NHLBI NIH HHS R01 HL131181NHLBI NIH HHS R35 HL140027NIDDK NIH HHS R37 DK053832NINDS NIH HHS R01 NS110656
6 · The paper itself

Abstract

The phosphoinositide, phosphatidylinositol 4,5-bisphosphate (PIP

Indexed as

AnimalsEndothelial CellsEndothelium, VascularHumansIon ChannelsMuscle, Smooth, VascularMyocytes, Smooth MusclePhosphatidylinositol 4,5-DiphosphateVascular DiseasesIon ChannelsPhosphatidylinositol 4,5-Diphosphateendothelial cellGPCRion channelPIP2smooth muscle cell

Identifiers

PMID32764146
PMCPMC7456132
OpenAlexW3047124117

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.