Evidence map›Paper›PMID 32763972›Full record

ArticleThe Journal of biological chemistry2020

Point mutations that inactivate MGAT4D-L, an inhibitor of MGAT1 and complex

Ayodele Akintayo, Joshua Mayoral, Masahiro Asada, Jian Tang, Subha Sundaram, Pamela Stanley

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ayodele AkintayoDept. of Cell Biology, Albert Einstein College of Medicine, New York, New York.
Joshua MayoralDept. of Cell Biology, Albert Einstein College of Medicine, New York, New York.
Masahiro AsadaDept. of Cell Biology, Albert Einstein College of Medicine, New York, New York.
Jian TangDept. of Cell Biology, Albert Einstein College of Medicine, New York, New York.
Subha SundaramDept. of Cell Biology, Albert Einstein College of Medicine, New York, New York.
Pamela StanleyDept. of Cell Biology, Albert Einstein College of Medicine, New York, New York pamela.stanley@einsteinmed.org.ORCID 0000-0001-5704-3747
Albert Einstein College of Medicine · US

Funding

Lectin Resistant Tumor Cells And Functional GlycomicsR01CA036434 · NCI · YESHIVA UNIVERSITY · PI STANLEY, PAMELA M · 1985 to 2011
$4.9M
Lectin Resistant Tumor Cells and Functional GlycomicsR01GM105399 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STANLEY, PAMELA M · 2013 to 2022
$3.6M
NIGMS NIH HHS R01 GM105399
6 · The paper itself

Abstract

The membrane-bound, long form of MGAT4D, termed MGAT4D-L, inhibits MGAT1 activity in transfected cells and reduces the generation of complex

Indexed as

Drosophila ProteinsMembrane ProteinsN-AcetylglucosaminyltransferasesPoint MutationAmino Acid SequenceAnimalsCHO CellsCricetulusDrosophila melanogasterEnzyme InhibitorsHL-60 CellsHumansMannose-Binding LectinsPlant LectinsPolysaccharidesProtein BindingDrosophila ProteinsEnzyme InhibitorsMannose-Binding LectinsMembrane ProteinsMGAT1 protein, DrosophilaMGAT1 protein, humanMGAT4D protein, humanN-AcetylglucosaminyltransferasesPlant LectinsPolysaccharidessnowdrop lectinflow cytometryglycosylation inhibitorglycosyltransferaseGNAlectinMGAT1MGAT4DMGAT4D-Lmutagenesismutational analysisN-glycans

Identifiers

PMID32763972
PMCPMC7549026
OpenAlexW3048029308

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.