Evidence map›Paper›PMID 32763966›Full record

ArticleOpen heart2020

Left ventricular mass and myocardial scarring in women with hypertensive disorders of pregnancy.

Odayme Quesada, Ki Park, Janet Wei, Eileen Handberg, Chrisandra Shufelt, Margo Minissian, Galen Cook-Wiens, Parham Zarrini, Christine Pacheco, Balaji Tamarappoo and 4 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Open heart, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Odayme Quesada *Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Ki Park *Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Janet WeiSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Eileen HandbergCardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Chrisandra ShufeltSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Margo MinissianSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Galen Cook-WiensBiostatistics and Bioinformatics Research Center, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Parham ZarriniSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Christine PachecoSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.ORCID 0000-0003-1355-2632
Balaji TamarappooSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Louise E J ThomsonS Mark Taper Foundation Imaging Center, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Daniel S BermanS Mark Taper Foundation Imaging Center, Cedars-Sinai Medical Center, Los Angeles, California, USA.
Carl J PepineCardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Noel Bairey MerzSmidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA merz@cshs.org.ORCID 0000-0002-9933-5155
Cedars-Sinai Medical Center · USUniversity of Florida · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
UCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0M
UF Clinical and Translational Science AwardUL1TR000064 · NCATS · UNIVERSITY OF FLORIDA · PI NELSON, DAVID R · 2012 to 2014
$12.2M
Renin Angiotensin for Coronary Microvascular DysfunctionU01HL064924 · NHLBI · UNIVERSITY OF FLORIDA · PI PEPINE, CARL J · 2001 to 2005
$2.0M
Functional MRI of the pharyngeal airwayR01HL068162 · NHLBI · UNIVERSITY OF ARIZONA · PI FREGOSI, RALPH FRANK · 2003 to 2005
$899k
Cardiac Autonomic Function in WomenK23HL105787 · NHLBI · EMORY UNIVERSITY · PI MEHTA, PUJA KIRAN · 2012 to 2016
$813k
Hypertensive Disorders of Pregnancy: Pathways to Future Cardiovascular DiseaseK23HL151867 · NHLBI · THE CHRIST HOSPITAL · PI QUESADA, ODAYME · 2020 to 2024
$799k
Immunologic Basis of Coronary Disease in WomenU01HL064914 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2001 to 2002
$674k
ISCHEMIC HEART DISEASE IN WOMEN-CLINICAL CENTERN01HV068161 · HV · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROGERS, WILLIAM J · 1996 to 2000
$245k
EVAL OF ISCHEMIC HEART DISEASE IN WOMEN-CLINICAL CTRN01HV068164 · HV · ALLEGHENY-SINGER RESEARCH INSTITUTE · PI REICHEK, NATHANIEL · 1996 to 2001
–
NCATS NIH HHS UL1 TR000064NCATS NIH HHS UL1 TR000124NCATS NIH HHS UL1 TR001881NHLBI NIH HHS K23 HL105787NHLBI NIH HHS K23 HL151867NHLBI NIH HHS N01 HV068161NHLBI NIH HHS N01 HV068164NHLBI NIH HHS N01HV68162NHLBI NIH HHS N01HV68163NHLBI NIH HHS U01 HL064914NHLBI NIH HHS U01 HL064924
6 · The paper itself

Abstract

aimsHypertensive disorders of pregnancy (HDP) predict future cardiovascular events. We aim to investigate relations between HDP history and subsequent hypertension (HTN), myocardial structure and function, and late gadolinium enhancement (LGE) scar. METHODS AND

resultsWe evaluated a prospective cohort of women with suspected ischaemia with no obstructive coronary artery disease (INOCA) who underwent stress/rest cardiac magnetic resonance imaging (cMRI) with LGE in the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction study. Self-reported history of pregnancy and HDP (gestational HTN, pre-eclampsia, toxaemia and eclampsia) were collected at enrollment. In our cohort of 346, 20% of women report a history of HDP. HDP history was associated with 3.2-fold increased odds of HTN. Women with a history of

conclusionIn a high-risk cohort of women with suspected INOCA, 20% had a history of HDP. Women with HDP history were more likely to develop HTN. Our study demonstrates higher LV mass in women with HDP and concomitant HTN. Although the presence of LGE scar was not different in women with and without HDP history, we observed a trend towards larger scar size in women with HDP. Future studies are needed to better assess the relationship of HDP and cardiac morphology and LGE scarring in a larger cohort of women.

Indexed as

Hypertension, Pregnancy-InducedVentricular Function, LeftVentricular RemodelingAdultAgedBlood PressureContrast MediaFemaleFibrosisFloridaHeart Disease Risk FactorsHumansHypertensionLos AngelesMagnetic Resonance Imaging, CineMiddle AgedContrast Mediacoronary artery diseasehypertensionMRIrisk factors

Identifiers

PMID32763966
PMCPMC7412584
OpenAlexW3047633167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.