Evidence map›Paper›PMID 32763440›Full record

SynthesisInfection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases2020

A systematic review of re-detectable positive virus nucleic acid among COVID-19 patients in recovery phase.

Zhiru Gao, Yinghui Xu, Ye Guo, Dongsheng Xu, Li Zhang, Xu Wang, Chao Sun, Shi Qiu, Kewei Ma

Abstract readSystematic Review
In one paragraph

Synthesis in Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Review
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  13. A Role for Extracellular Vesicles in SARS-CoV-2 Therapeutics and Prevention.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2021
    Review
  14. Article
  15. Article
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  18. Recurrence of SARS-CoV-2 viral RNA in recovered COVID-19 patients: a narrative review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiru GaoCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Yinghui XuCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Ye GuoCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Dongsheng XuCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Li ZhangDepartment of Radiology, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Xu WangCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Chao SunCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Shi QiuCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China.
Kewei MaCancer Center, The First Hospital of Jilin University, Changchun, Jilin 130021, China. Electronic address: makw@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A large number of coronavirus disease 2019 (COVID-19) patients have been cured and discharged due to timely and effective treatments. While some discharged patients have been found re-positive nucleic acid again in the recovery phase. Until now, there is still a great challenge to its infectivity and the specific potential mechanism which needs further discussion. However, more intensive attention should be paid to the prognosis of recovered patients. In this review, we mainly focus on the characteristics, potential reasons, infectivity, and outcomes of re-detectable positive patients, thereby providing some novel insights into the cognition of COVID-19.

Indexed as

COVID-19COVID-19 Drug TreatmentHumansPatient DischargePrognosisRecovery of FunctionRNA, ViralSARS-CoV-2Virus LatencyRNA, ViralCharacteristicCOVID-19OutcomeRecovered patientsSARS-CoV-2

Identifiers

PMID32763440
PMCPMC7403029

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.