ArticleAnalytical biochemistry2022
Recent advances in aptamer applications for analytical biochemistry.
Article in Analytical biochemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- A low-background, high-output electrochemiluminescence aptasensor for ultrasensitive detection of small biomolecules.Mikrochimica acta · 2026Article
- High-affinity ssDNA aptamer and chemiluminescent aptasensor for TIMP-1 detection in human serum.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2025Article
- Aptamer based immunotherapy: a potential solid tumor therapeutic.Frontiers in immunology · 2025Review
- A clenbuterol detection method based on magnetic separation up-conversion fluorescent probe.Food chemistry: X · 2024Article
- Bio-Tailored Sensing at the Nanoscale: Biochemical Aspects and Applications.Sensors (Basel, Switzerland) · 2023Review
- Chemically modified aptamers for improving binding affinity to the target proteinsFrontiers in cell and developmental biology · 2023Review
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Abstract
Aptamers are typically defined as relatively short (20-60 nucleotides) single-stranded DNA or RNA molecules that bind with high affinity and specificity to various types of targets. Aptamers are frequently referred to as "synthetic antibodies" but are easier to obtain, less expensive to produce, and in several ways more versatile than antibodies. The beginnings of aptamers date back to 1990, and since then there has been a continual increase in aptamer publications. The intent of the present account was to focus on recent original research publications, i.e., those appearing in 2019 through April 2020, when this account was written. A Google Scholar search of this recent literature was performed for relevance-ranking of articles. New methods for selection of aptamers were not included. Nine categories of applications were organized and representative examples of each are given. Finally, an outlook is offered focusing on "faster, better, cheaper" application performance factors as key drivers for future innovations in aptamer applications.
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Registered trials
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