Evidence map›Paper›PMID 32763184›Full record

ArticleCell2020

Finding a Needle in a Haystack: Identification of a Beige Fat Progenitor.

Claudio J Villanueva

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Claudio J VillanuevaDepartment of Integrative Biology and Physiology, Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. Electronic address: cvillanueva@ucla.edu.
University of California, Los Angeles · US

Funding

Role of TLE3 in the transcriptional regulation of beige adipocytesR01DK103930 · NIDDK · UNIVERSITY OF UTAH · PI VILLANUEVA, CLAUDIO J · 2015 to 2019
$1.7M
NIDDK NIH HHS R01 DK103930
6 · The paper itself

Abstract

Oguri and colleagues use single-cell RNA sequencing to identify a beige adipocyte precursor cell that gives rise to thermogenic adipocytes in subcutaneous adipose tissue. These beige fat progenitors are marked by PDGFRα, Sca1, and CD81 and proliferate upon activation of FAK-signaling in response to the cold and irisin.

Indexed as

Adipocytes, BeigeAdipose Tissue, BeigeSignal TransductionStem CellsThermogenesis

Identifiers

PMID32763184
OpenAlexW3047527798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.