Evidence map›Paper›PMID 32762846›Full record

ArticleeLife2020

Mechanisms underlying genome instability mediated by formation of foldback inversions in

Bin-Zhong Li, Christopher D Putnam, Richard David Kolodner

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Assessment and Mitigation of CRISPR-Cas9-Induced Nontargeted Translocations.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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  9. Palindromes in DNA-A Risk for Genome Stability and Implications in Cancer.International journal of molecular sciences · 2021
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Bin-Zhong LiLudwig Institute for Cancer Research, University of California School of Medicine, San Diego, San Diego, United States.
Christopher D PutnamLudwig Institute for Cancer Research, University of California School of Medicine, San Diego, San Diego, United States.ORCID 0000-0002-6145-1265
Richard David KolodnerLudwig Institute for Cancer Research, University of California School of Medicine, San Diego, San Diego, United States.ORCID 0000-0002-4806-8384
University of California San Diego · USLudwig Cancer Research · US

Funding

ENZYMATIC MECHANISMS OF GENETIC RECOMBINATIONR01GM026017 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard D Kolodner · 1985 to 2026
$10.5M
ENZYMATIC MECHANISMS OF GENETIC RECOMBINATIONR37GM026017 · NIGMS · UNIVERSITY OF CALIFORNIA SAN DIEGO · PI KOLODNER, RICHARD D · 1992 to 2001
$759k
NIGMS NIH HHS R01 GM026017NIGMS NIH HHS R37 GM026017
6 · The paper itself

Abstract

Foldback inversions, also called inverted duplications, have been observed in human genetic diseases and cancers. Here, we used a

Indexed as

Chromosome InversionGenomic InstabilityChromosomes, FungalDNA Breaks, Double-StrandedGene RearrangementGenome, FungalHomologous RecombinationSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSaccharomyces cerevisiae Proteinschromosomesdna repairgene expressiongenome rearrangementS. cerevisiaetranslocationwhole genome sequencing

Identifiers

PMID32762846
PMCPMC7467729
OpenAlexW3047826374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.