ArticleBMC medicine2020
Spatial modes for transmission of chikungunya virus during a large chikungunya outbreak in Italy: a modeling analysis.
Article in BMC medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Autochthonous transmission patterns of dengue virus serotype 2 in Italy: evidence from outbreaks in 2024.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2026Article
- Predicting the global risk of chikungunya virus under climate change using ensemble species distribution models.Frontiers in cellular and infection microbiology · 2026Article
- A systematic review and meta-analysis of mosquito arboviral infections detected through xenosurveillance in Africa: A focus on West Nile, Rift Valley fever, and chikungunya virus infections.Current research in parasitology & vector-borne diseases · 2026Review
- Chikungunya virus infection in Italy: epidemiology, climate change implications and public health recommendations.Frontiers in public health · 2026Article
- Assessing risks of dengue, chikungunya and Zika transmission associated to Aedes albopictus in Chania, Greece, 2017-2018.PLoS neglected tropical diseases · 2025Article
- Predictability of infectious disease outbreak severity: Chikungunya as a case study.Science advances · 2025Article
- Risk assessment and perspectives of local transmission of chikungunya and dengue in Italy, a European forerunner.Nature communications · 2025Article
- Transmission of autochthonous Aedes-borne arboviruses and related public health challenges in Europe 2007-2023: a systematic review and secondary analysis.The Lancet regional health. Europe · 2025Article
- Quantifying infectious disease epidemic risks: A practical approach for seasonal pathogens.PLoS computational biology · 2025Article
- Strategic vaccination responses to Chikungunya outbreaks in Rome: Insights from a dynamic transmission model.PLoS neglected tropical diseases · 2024Article
- Article
- The 2013 Chikungunya outbreak in the Caribbean was structured by the network of cultural relationships among islands.Royal Society open science · 2023Article
- Reporting delays of chikungunya cases during the 2017 outbreak in Lazio region, Italy.PLoS neglected tropical diseases · 2023Article
- How habitat factors affect an Aedes mosquitoes driven outbreak at temperate latitudes: The case of the Chikungunya virus in Italy.PLoS neglected tropical diseases · 2023Article
- Diel activity patterns of vector mosquito species in the urban environment: Implications for vector control strategies.PLoS neglected tropical diseases · 2023Article
- Estimation of the incubation period and generation time of SARS-CoV-2 Alpha and Delta variants from contact tracing data.Epidemiology and infection · 2022Article
- Intrinsic generation time of the SARS-CoV-2 Omicron variant: An observational study of household transmission.The Lancet regional health. Europe · 2022Article
- Inferring person-to-person networks of Plasmodium falciparum transmission: are analyses of routine surveillance data up to the task?Malaria journal · 2022Article
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14 authors.
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Abstract
backgroundThe spatial spread of many mosquito-borne diseases occurs by focal spread at the scale of a few hundred meters and over longer distances due to human mobility. The relative contributions of different spatial scales for transmission of chikungunya virus require definition to improve outbreak vector control recommendations.
methodsWe analyzed data from a large chikungunya outbreak mediated by the mosquito Aedes albopictus in the Lazio region, Italy, consisting of 414 reported human cases between June and November 2017. Using dates of symptom onset, geographic coordinates of residence, and information from epidemiological questionnaires, we reconstructed transmission chains related to that outbreak.
resultsFocal spread (within 1 km) accounted for 54.9% of all cases, 15.8% were transmitted at a local scale (1-15 km) and the remaining 29.3% were exported from the main areas of chikungunya circulation in Lazio to longer distances such as Rome and other geographical areas. Seventy percent of focal infections (corresponding to 38% of the total 414 cases) were transmitted within a distance of 200 m (the buffer distance adopted by the national guidelines for insecticide spraying). Two main epidemic clusters were identified, with a radius expanding at a rate of 300-600 m per month. The majority of exported cases resulted in either sporadic or no further transmission in the region.
conclusionsEvidence suggest that human mobility contributes to seeding a relevant number of secondary cases and new foci of transmission over several kilometers. Reactive vector control based on current guidelines might allow a significant number of secondary clusters in untreated areas, especially if the outbreak is not detected early. Existing policies and guidelines for control during outbreaks should recommend the prioritization of preventive measures in neighboring territories with known mobility flows to the main areas of transmission.
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