ReviewBMC oral health2020
Pathogenesis, diagnosis and management of dentin hypersensitivity: an evidence-based overview for dental practitioners.
Review in BMC oral health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06685016 (Evaluation of Dental and Periodontal Health After Interproximal Enamel Reduction, in Patients in Orthodontic Treatment With Clear Aligners, and Comparison Between Laser Diode and Sodium Fluoride for the Treatment of Dentin Hypersensitivity), which is not on this map. Cited by 86 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Evaluation of Dental and Periodontal Health After Interproximal Enamel Reduction, in Patients in Orthodontic Treatment With Clear Aligners, and Comparison Between Laser Diode and Sodium Fluoride for the Treatment of Dentin Hypersensitivity
Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 211 citations in OpenAlex.
- Survey methods contributing to the difference of dentin hypersensitivity prevalence among publications between 1998 and 2022: a research-on-research study.BMC oral health · 2025Pooled it
- The Decision Tree for Clinical Management of Dentin Hypersensitivity. A Consensus Report.Oral health & preventive dentistry · 2022Pooled it
- Clinical effectiveness of theobromine, Remin Pro, and their combination in managing dentin hypersensitivity: a randomized clinical trial.BMC oral health · 2026Trial
- Anhydrous stannous fluoride toothpaste in dentin hypersensitivity: clinician-assessed and patient-reported outcomes from two controlled trials.Clinical oral investigations · 2026Trial
- Effect of different material protocols on the control of dentin hypersensitivity: a split-mouth randomized controlled clinical trial.Clinical oral investigations · 2026Trial
- Longevity of different in-office treatments for dentin hypersensitivity: A 6-month randomized and parallel clinical trial.PloS one · 2026Trial
- Effect of 1064 nm Nd:YAG laser or 15% calcium sodium phosphosilicate prophy paste on dentin hypersensitivity over six months: a double-blind randomized clinical trial.Lasers in medical science · 2025Trial
- Effect of photobiomodulation on dentin hypersensitivity: a randomized controlled double-blind clinical trial.Clinical oral investigations · 2025Trial
- Clinical evaluation of the effect of 980 nm diode laser and fluoride varnish on dentin hypersensitivity.Brazilian oral research · 2025Trial
- Desensitizing efficacy of a universal dentin adhesive containing mesoporous bioactive glass on dentin hypersensitivity: a randomized clinical trial with a split-mouth model.Scientific reports · 2024Trial
- Efficacy of different in-office treatments for dentin hypersensitivity: randomized and parallel clinical trial.Brazilian dental journal · 2024Trial
- A novel treatment based on powder jet deposition technique for dentin hypersensitivity: a randomized controlled trial.BMC oral health · 2023Trial
- Bonding strategy of a universal adhesive system containing chitosan: influence on dentin permeability, and effect on adhesive layer micromorphology.Acta odontologica latinoamericana : AOL · 2022Trial
- Prevalence and oral hygiene-related correlates of self-reported dentin hypersensitivity among Egyptian adults: a cross-sectional study.BMC oral health · 2026Article
- Effects of desensitizing treatments on acid-etched dentin: debris precipitation, bond strength and tag formation.Odontology · 2026Article
- Comparative Effects of Experimental Bioactive Glasses on Dentin Permeability and Tubule Occlusion In Vitro.Journal of functional biomaterials · 2026Article
- Assessment of dentinal fluid flow reduction following simulated brushing with desensitizing toothpastes using sub-nanoliter fluid flow measurement system.BMC oral health · 2026Article
- Article
- Hydrostatic pressure promotes odontoblast differentiation via PIEZO1-dependent activation of RUNX2 and WNT16 in SHED.Scientific reports · 2026Article
- Dentin hypersensitivity, an enigma revisited: Mechanisms, diagnosis and therapeutic advances.Journal of conservative dentistry and endodontics · 2026Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Though dentin hypersensitivity (DHS) is one of the most common complaints from patients in dental clinics, there are no universally accepted guidelines for differential diagnosis as well as selection of reliable treatment modalities for this condition. The neurosensory mechanisms underlying DHS remain unclear, but fluid movements within exposed dentinal tubules, i.e., the hydrodynamic theory, has been a widely accepted explanation for DHS pain. As several dental conditions have symptoms that mimic DHS at different stages of their progression, diagnosis and treatment of DHS are often confusing, especially for inexperienced dental practitioners. In this paper we provide an up-to-date review on risk factors that play a role in the development and chronicity of DHS and summarize the current principles and strategies for differential diagnosis and management of DHS in dental practices. We will outline the etiology, predisposing factors and the underlying putative mechanisms of DHS, and provide principles and indications for its diagnosis and management. Though desensitization remains to be the first choice for DHS for many dental practitioners and most of desensitizing agents reduce the symptoms of DHS by occluding patent dentinal tubules, the long-term outcome of such treatment is uncertain. With improved understanding of the underlying nociceptive mechanisms of DHS, it is expected that promising novel therapies will emerge and provide more effective relief for patients with DHS.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.