ArticleAmerican journal of physiology. Heart and circulatory physiology2020
Synergy in the heart: RV systolic function plays a key role in optimizing LV performance during exercise.
Article in American journal of physiology. Heart and circulatory physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Dynamic right ventricular and atrial volume responses to exercise in endurance-trained and untrained healthy individuals.PloS one · 2026Article
- Machine-learning-based prediction of respiratory flow and lung volume from real-time cardiac MRI using MR-compatible spirometry.Medical physics · 2025Article
- Sports activities and cardiovascular system change.Physiological research · 2023Review
- Article
- Exercise and hypoxia unmask pulmonary vascular disease and right ventricular dysfunction in a 10- to 12-week-old swine model of neonatal oxidative injury.The Journal of physiology · 2022Article
- Validation and quantification of left ventricular function during exercise and free breathing from real-time cardiac magnetic resonance images.Scientific reports · 2022Article
- Inhaled nitric oxide does not improve maximal oxygen consumption in endurance trained and untrained healthy individuals.European journal of applied physiology · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
Abstract
The right ventricle (RV) is often overlooked in the evaluation of cardiac performance and treatment of left ventricular (LV) heart diseases. However, recent evidence suggests the RV may play an important role in maintaining systemic cardiac function and delivering stroke volume (SV). We used exercise cardiac magnetic resonance and biomechanical modeling to investigate the role of the RV in LV stroke volume regulation. We studied SV augmentation during exercise by pharmacologically inducing negative chronotropy (sHRi) in healthy volunteers and investigating training-induced SV augmentation in endurance athletes. SV augmentation during exercise after sHRi is achieved differently in the two ventricles. In the RV, the larger SV is driven by increasing contraction down to lower end-systolic volume (ESV;
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.