Evidence map›Paper›PMID 32762403›Full record

ReviewThe Journal of international medical research2020

Jaundice may be the only clinical manifestation of primary hepatosplenic diffuse large B-cell lymphoma: a case report and literature review.

Xue Shi, Tingting Zhang, Hong Xu, Xiaoying Zhang, Hongguo Zhao, Xiaodan Liu, Fang Hou, Guangjie Yang, Zhihe Liu

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in The Journal of international medical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. CD5Discover oncology · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xue ShiDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Tingting ZhangDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0001-8598-6769
Hong XuDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaoying ZhangDepartment of Emergency, The Affiliated Hospital of Qingdao University, Qingdao, China.
Hongguo ZhaoDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Xiaodan LiuDepartment of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Fang HouDepartment of Hematology Research Laboratory, The Affiliated Hospital of Qingdao University, Qingdao, China.
Guangjie YangDepartment of PET/CT Center, The Affiliated Hospital of Qingdao University, Qingdao, China.
Zhihe LiuDepartment of Lymphoma, The Affiliated Hospital of Qingdao University, Qingdao, China.ORCID https://orcid.org/0000-0002-9264-094X
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 64-year old Chinese male patient was admitted to our hospital because of severe jaundice that persisted for 2 months. No swollen lymph nodes or hepatosplenomegaly was detected on physical examination. His laboratory data indicated high levels of direct bilirubin, alkaline phosphatase, aspartate aminotransferase, and alanine aminotransferase. No abnormality was revealed on abdominal computed tomography (CT). However, positron emission tomography (PET)-CT revealed diffuse hypermetabolism in the liver and spleen. Ultimately, liver biopsy guided by PET-CT was performed, revealing that atypical lymphocytes diffusely infiltrated the liver. The immunohistochemical analysis demonstrated that the tumor cells were positive for CD20, Bcl-2, Bcl-6, MUM1, and c-Myc but negative for CD3, CD4, CD8, and CD10. Based on these findings, this patient was diagnosed with primary hepatosplenic diffuse large B-cell lymphoma. After the definite diagnosis, he received chemotherapy and remained in good health as of September 2019.

Indexed as

JaundiceLymphoma, Large B-Cell, DiffuseBiopsyHumansMaleMiddle AgedPositron Emission Tomography Computed TomographyTomography, X-Ray Computedcomputed tomographyDiffuse large B-cell lymphomajaundiceliverpositron emission tomographyprimary hepatosplenic lymphomaR-CHOP

Identifiers

PMID32762403
PMCPMC7416148
OpenAlexW3048259335

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.