Evidence map›Paper›PMID 32762296›Full record

ArticleThyroid : official journal of the American Thyroid Association2021

Thyroid Hormone Receptor α Mutations Cause Heart Defects in Zebrafish.

Cho Rong Han, Hui Wang, Victoria Hoffmann, Patricia Zerfas, Michael Kruhlak, Sheue-Yann Cheng

Open access · greenAbstract readVideo-Audio Media
In one paragraph

Article in Thyroid : official journal of the American Thyroid Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Experimentally Manipulating the Thyroid Hormone Axis in Zebrafish.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  7. Article
  8. Article
  9. Morphological and Functional Colonic Defects Caused by a Mutated Thyroid Hormone Receptor α.Thyroid : official journal of the American Thyroid Association · 2023
    Article
  10. Sarcomere maturation: function acquisition, molecular mechanism, and interplay with other organelles.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  11. Best Achievements in Translational and Basic Thyroidology in 2020.Endocrinology and metabolism (Seoul, Korea) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Cho Rong HanLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Hui WangLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Victoria HoffmannDiagnostic and Research Services Branch, Office of Research Services, National Institutes of Health, Bethesda, Maryland, USA.
Patricia ZerfasDiagnostic and Research Services Branch, Office of Research Services, National Institutes of Health, Bethesda, Maryland, USA.
Michael KruhlakLaboratory of Cancer Biology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Sheue-Yann ChengLaboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
National Institutes of Health · US

Funding

CCR Microscopy CoreZICBC010858 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KRUHLAK, MICHAEL · 2009 to 2025
$14.8M
Thyroid Hormone Receptors in Health and DiseaseZIABC008752 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHENG, SHEUE-YANN · 2009 to 2025
$12.9M
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAnimalsAnimals, Genetically ModifiedBradycardiaGenetic Predisposition to DiseaseHeart Defects, CongenitalMyocardial ContractionMyocardiumThyroid Hormone Receptors alphaThyroid Hormone Receptors betaVentricular FunctionZebrafishZebrafish ProteinsThyroid Hormone Receptors alphaThyroid Hormone Receptors betaZebrafish Proteinsblood speedbradycardiacontractilityheart defectsmutationszebrafish, TRα

Identifiers

PMID32762296
PMCPMC7891307
OpenAlexW3047692694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.