Evidence map›Paper›PMID 32761981›Full record

Observational studyEuropean journal of neurology2020

Impact of COVID-19 outbreak in reperfusion therapies of acute ischaemic stroke in northwest Spain.

H Tejada Meza, Á Lambea Gil, A Sancho Saldaña, M Martínez-Zabaleta, E Garmendia Lopetegui, E López-Cancio Martínez, M Castañón Apilánez, M Herrera Isasi, J Marta Enguita, B Gómez-Vicente and 25 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in European journal of neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Impact of the COVID-19 pandemic on head and neck cancer diagnosis: data from a single referral center, South Tyrol, northern Italy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  6. Social Distancing, Stroke Admissions and Stroke Mortality During the COVID-19 Pandemic: A Multicenter, Longitudinal Study.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2022
    Article
  7. Article
  8. Treat COVID-19, but Not Only COVID-19: Stroke Matters as Well.Cerebrovascular diseases (Basel, Switzerland) · 2022
    Article
  9. Article
  10. Observational
  11. Article
  12. Impact on polytrauma patient prehospital care during the first wave of the COVID-19 pandemic: a cross-sectional study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2021
    Article
  13. Observational
  14. Article
  15. Article
  16. Review
  17. Changes in Prehospital Stroke Care and Stroke Mimic Patterns during the COVID-19 Lockdown.International journal of environmental research and public health · 2021
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 17 institutions in 1 country.

H Tejada MezaStroke Unit, Department of Neurology, Hospital Universitario Miguel Servet, Zaragoza, Spain.ORCID 0000-0002-6506-1037
Á Lambea GilStroke Unit, Department of Neurology, Hospital Universitario Miguel Servet, Zaragoza, Spain.ORCID 0000-0003-1785-9201
A Sancho SaldañaStroke Unit, Department of Neurology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
M Martínez-ZabaletaDepartment of Neurology, Donostia University Hospital, San Sebastián, Spain.
E Garmendia LopeteguiDepartment of Neuroradiology, Donostia University Hospital, San Sebastián, Spain.
E López-Cancio MartínezDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
M Castañón ApilánezDepartment of Neurology, Hospital Universitario Central de Asturias, Oviedo, Spain.
M Herrera IsasiDepartment of Neurology, Complejo Hospitalario de Navarra, Pamplona, Spain.
J Marta EnguitaDepartment of Neurology, Complejo Hospitalario de Navarra, Pamplona, Spain.
B Gómez-VicenteDepartment of Neurology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
J F ArenillasDepartment of Neurology, Hospital Clínico Universitario de Valladolid, Valladolid, Spain.
N Arenaza BasterrecheaStroke Unit, Department of Neurology, Hospital Universitario de Araba, Vitoria, Spain.
J J Timiraos FernándezStroke Unit, Department of Neurology, Hospital Universitario de Araba, Vitoria, Spain.
J Sánchez HerreroDepartment of Neurology, Complejo Hospitalario Universitario de Vigo, Vigo, Spain.
J L Maciñeiras MonteroDepartment of Neurology, Complejo Hospitalario Universitario de Vigo, Vigo, Spain.
M Castellanos RodrigoDepartment of Neurology, Complexo Hospitalario Universitario A Coruña / A Coruña Biomedical Research Insitute, A Coruña, Spain.
D Fernández-CoudDepartment of Neurology, Complexo Hospitalario Universitario A Coruña / A Coruña Biomedical Research Insitute, A Coruña, Spain.
I Casado MenéndezStroke Unit, Department of Neurology, Hospital Universitario de Cabueñes, Gijón, Spain.
M T Temprano FernándezStroke Unit, Department of Neurology, Hospital Universitario de Cabueñes, Gijón, Spain.
M FreijoNeurovascular Department Biocruces Bizkaia Health Research Institute, Osakidetza, Hospital Universitario Cruces, Barakaldo, Spain.
A LunaNeurovascular Department Biocruces Bizkaia Health Research Institute, Osakidetza, Hospital Universitario Cruces, Barakaldo, Spain.
E J Palacio PortillaDepartment of Neurology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
Y Jiménez LópezDepartment of Neurology, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
E Rodríguez-CastroDepartment of Neurology, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
M Rodríguez-YáñezDepartment of Neurology, Complejo Hospitalario Universitario de Santiago, Santiago de Compostela, Spain.
J Tejada GarcíaDepartment of Neurology, Complejo Asistencial Universitario de León, León, Spain.
I Beltrán RodríguezDepartment of Neurology, Complejo Hospitalario de Navarra, Pamplona, Spain.
F Julián-VillaverdeDepartment of Neurology, Hospital San Pedro, Logroño, Spain.
M P Moreno GarcíaDepartment of Neurology, Hospital San Pedro, Logroño, Spain.
J M Trejo Gabriel-GalánDepartment of Neurology, Complejo Asistencial Universitario de Burgos, Burgos, Spain.
A Echavarría IñiguezDepartment of Neurology, Complejo Asistencial Universitario de Burgos, Burgos, Spain.
C Pérez LázaroDepartment of Neurology, Hospital Clínico Lozano Blesa, Zaragoza, Spain.
M P Navarro PérezDepartment of Neurology, Hospital Clínico Lozano Blesa, Zaragoza, Spain.ORCID 0000-0001-6370-218X
J Marta MorenoStroke Unit, Department of Neurology, Hospital Universitario Miguel Servet, Zaragoza, Spain.
NORDICTUS Investigators
Hospital Universitario Miguel Servet · ESComplejo Hospitalario de Navarra · ESBioCruces Health research Institute · ESBiogipuzkoa Health Research Institute · ESComplejo Hospitalario Universitario de Santiago · ESComplexo Hospitalario Universitario A Coruña · ESHospital Clínico Universitario Lozano Blesa · ESHospital San Pedro · ESHospital Universitario Araba · ESHospital Universitario Central de Asturias · ESHospital Universitario de Burgos · ESHospital Universitario De Cabueñes · ESMarqués de Valdecilla University Hospital · ESUniversity Hospital Complex Of Vigo · ESComplejo Asistencial Universitario de Palencia · ESHospital Clínico Universitario de Valladolid · ESUniversidad de Valladolid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSpain has been one of the countries more heavily stricken by SARS-CoV-2, which has had huge implications for stroke care. The aim was to analyse the impact of the COVID-19 epidemic outbreak on reperfusion therapies for acute ischaemic stroke in the northwest of Spain.

methodsThis was a Spanish multicentre retrospective observational study based on data from tertiary hospitals of the NORDICTUS network. All patients receiving reperfusion therapy for ischaemic stroke between 30 December 2019 and 3 May 2020 were recorded, and their baseline, clinical and radiological characteristics, extra- and intra-hospital times of action, Code Stroke activation pathway, COVID-19 status, reperfusion rate, and short-term outcome before and after the setting of the emergency state were analysed.

resultsA total of 796 patients received reperfusion therapies for ischaemic stroke. There was a decrease in the number of patients treated per week (46.5 patients per week vs. 39.0 patients per week, P = 0.043) and a delay in out-of-hospital (95.0 vs. 110.0 min, P = 0.001) and door-to-needle times (51.0 vs. 55.0, P = 0.038). Patients receiving endovascular therapy obtained less successful reperfusion rates (92.9% vs. 86.6%, P = 0.016). COVID-19 patients had more in-hospital mortality.

conclusionA decrease in the number of patients benefiting from reperfusion therapies was found, with a delay in out-of-hospital and door-to-needle times and worse reperfusion rates in northwest Spain. COVID-19 patients had more in-hospital mortality.

Indexed as

COVID-19PandemicsReperfusionAdultAgedAged, 80 and overEmergency Medical ServicesEndovascular ProceduresFemaleHumansIschemic StrokeLength of StayMaleMiddle AgedPatient AdmissionRegistriesacute stroke therapycerebral infarctionCOVID-19ischaemic strokeSpainthrombectomythrombolysis

Identifiers

PMID32761981
PMCPMC7436392
OpenAlexW3048354488

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.