Evidence map›Paper›PMID 32761936›Full record

ArticleAlcoholism, clinical and experimental research2020

Can Alcohol Use Disorder Recovery Include Some Heavy Drinking? A Replication and Extension up to 9 Years Following Treatment.

Katie Witkiewitz, Matthew R Pearson, Adam D Wilson, Elena R Stein, Victoria R Votaw, Kevin A Hallgren, Stephen A Maisto, Julia E Swan, Frank J Schwebel, Arnie Aldridge and 2 more

Abstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Trial
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  11. Constructs derived from the addiction cycle predict alcohol use disorder treatment outcomes and recovery 3 years following treatment.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2023
    Article
  12. Article
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  15. Article
  16. Article
  17. Article
  18. What Is Recovery?Alcohol research : current reviews · 2020
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Katie WitkiewitzFrom the, Center on Alcoholism, Substance Abuse, and Addictions (CASAA), (KW, MRP, ADW, ERS, VRV, JES, FJS), University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0002-1086-3067
Matthew R PearsonFrom the, Center on Alcoholism, Substance Abuse, and Addictions (CASAA), (KW, MRP, ADW, ERS, VRV, JES, FJS), University of New Mexico, Albuquerque, New Mexico.
Adam D WilsonFrom the, Center on Alcoholism, Substance Abuse, and Addictions (CASAA), (KW, MRP, ADW, ERS, VRV, JES, FJS), University of New Mexico, Albuquerque, New Mexico.
Elena R SteinFrom the, Center on Alcoholism, Substance Abuse, and Addictions (CASAA), (KW, MRP, ADW, ERS, VRV, JES, FJS), University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0003-0404-250X
Victoria R VotawFrom the, Center on Alcoholism, Substance Abuse, and Addictions (CASAA), (KW, MRP, ADW, ERS, VRV, JES, FJS), University of New Mexico, Albuquerque, New Mexico.ORCID 0000-0002-4238-3383
Kevin A HallgrenUniversity of Washington, (KAH), Seattle, Washington.ORCID 0000-0001-8386-3984
Stephen A MaistoSyracuse University, (SAM), Syracuse, Washington.ORCID 0000-0001-5470-102X
Julia E SwanFrom the, Center on Alcoholism, Substance Abuse, and Addictions (CASAA), (KW, MRP, ADW, ERS, VRV, JES, FJS), University of New Mexico, Albuquerque, New Mexico.
Frank J SchwebelFrom the, Center on Alcoholism, Substance Abuse, and Addictions (CASAA), (KW, MRP, ADW, ERS, VRV, JES, FJS), University of New Mexico, Albuquerque, New Mexico.
Arnie AldridgeRTI International, (AA, GAZ), Research Triangle Park, North Carolina.
Gary A ZarkinRTI International, (AA, GAZ), Research Triangle Park, North Carolina.
Jalie A TuckerCenter for Behavioral Health Economic Research, (JAT), University of Florida, Gainesville, Florida.ORCID 0000-0003-1055-9038

Funding

Alcohol Research Training: Methods & MechanismsT32AA018108 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2010 to 2026
$5.6M
Precision Medicine and Recovery in a Telehealth Treatment Program for Alcohol Use DisorderR01AA022328 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2013 to 2026
$3.1M
Research and Mentoring on Alcohol Clinical and Human Laboratory ResearchK05AA016928 · NIAAA · SYRACUSE UNIVERSITY · PI MAISTO, STEPHEN A · 2008 to 2017
$2.1M
Developing a tool to assess, provide feedback, and facilitate discussion of mechanisms of change in frontline addiction treatmentK01AA024796 · NIAAA · UNIVERSITY OF WASHINGTON · PI HALLGREN, KEVIN A. · 2016 to 2020
$870k
Efficacy and neurobiological mechanisms of mobile-delivered cognitive retrainingK01AA023233 · NIAAA · UNIVERSITY OF NEW MEXICO · PI PEARSON, MATTHEW RYAN · 2014 to 2018
$832k
Validation of the Addictions Neuroclinical Assessment Among Diverse Individuals with Alcohol Use DisorderF31AA028971 · NIAAA · UNIVERSITY OF NEW MEXICO · PI STEIN, ELENA RACHEL · 2020 to 2021
$72k
The role of brain-derived neurotrophic factor in the link between physical activity and psychosocial recovery from alcohol use disorderF31AA026773 · NIAAA · UNIVERSITY OF NEW MEXICO · PI WILSON, ADAM DEFOREST · 2018 to 2019
$71k
NIAAA NIH HHS F31 AA026773NIAAA NIH HHS F31 AA028971NIAAA NIH HHS K01 AA023233NIAAA NIH HHS K01 AA024796NIAAA NIH HHS K05 AA016928NIAAA NIH HHS R01 AA022328NIAAA NIH HHS T32 AA018108
6 · The paper itself

Abstract

backgroundRecent research indicates some individuals who engage in heavy drinking following treatment for alcohol use disorder fare as well as those who abstain with respect to psychosocial functioning, employment, life satisfaction, and mental health. The current study evaluated whether these findings replicated in an independent sample and examined associations between recovery profiles and functioning up to 6 years later.

methodsData were from the 3-year and 7- to 9-year follow-ups of subsamples initially recruited for the COMBINE study (3-year follow-up: n = 694; 30.1% female, 21.0% non-White; 7- to 9-year follow-up: n = 127; 38.9% female, 27.8% non-White). Recovery at 3 years was defined by latent profile analyses including measures of health functioning, quality of life, employment, alcohol consumption, and cannabis and other drug use. Functioning at the 7- to 9-year follow-up was assessed using single items of self-rated general health, hospitalizations, and alcohol consumption.

resultsWe identified 4 profiles at the 3-year follow-up: (i) low-functioning frequent heavy drinkers (13.9%), (ii) low-functioning infrequent heavy drinkers (15.8%), (iii) high-functioning heavy drinkers (19.4%), and (iv) high-functioning infrequent drinkers (50.9%). At the 7- to 9-year follow-up, the 2 high-functioning profiles had the best self-rated health, and the high-functioning heavy drinking profile had significantly fewer hospitalizations than the low-functioning frequent heavy drinking profile.

conclusionsPrevious findings showing heterogeneity in recovery outcomes were replicated. Most treatment recipients functioned well for years after treatment, and a subset who achieved stable recovery engaged in heavy drinking and reported good health outcomes up to 9 years after treatment. Results question the long-standing emphasis on drinking practices as a primary outcome, as well as abstinence as a recovery criterion in epidemiologic and treatment outcome research and among stakeholder groups and funding/regulatory agencies. Findings support an expanded recovery research agenda that considers drinking patterns, health, life satisfaction, and functioning.

Indexed as

Alcohol AbstinenceAlcohol DrinkingEmploymentPersonal SatisfactionPsychosocial FunctioningQuality of LifeAdultAlcoholismFemaleFollow-Up StudiesHumansLatent Class AnalysisMaleMarijuana UseMental HealthMental Health RecoveryAlcohol TreatmentAlcohol Use DisorderCOMBINEMixture ModelsRecovery

Identifiers

PMID32761936
PMCPMC7540311

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.