ArticleJournal of orthopaedic research : official publication of the Orthopaedic Research Society2021
Sex and mechanism of injury influence knee joint loading symmetry during gait 6 months after ACLR.
Article in Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Differences in gait biomechanics in the first year after anterior cruciate ligament reconstruction: A systematic review.Clinical biomechanics (Bristol, Avon) · 2026Pooled it
- Advanced Biomaterial-Based In Vitro Osteoarthritis Models: Integrating Sex as a Biological Variable in Hormonal, Subchondral Bone, and Mechanobiological Pathways.Journal of functional biomaterials · 2026Review
- An exploratory study of relationships among morphological and mechanical properties of the patellar tendon and patient-reported outcomes after ACLR using BPTB autograft.Journal of experimental orthopaedics · 2026Article
- Comparison of Limb Loading Characteristics and Subjective Functional Outcomes Between Sexes After Anterior Cruciate Ligament Reconstruction.Journal of athletic training · 2024Article
- Regional healing trajectory of the patellar tendon after bone-patellar tendon-bone autograft harvest for anterior cruciate ligament reconstruction.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024Article
- Prolonged quadriceps latency during gait early after anterior cruciate ligament injury predicts radiographic knee osteoarthritis 6-years after anterior cruciate ligament reconstruction.Clinical biomechanics (Bristol, Avon) · 2024Article
- Males and females have different muscle activity patterns during gait after ACL injury and reconstruction.Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2022Article
- Identifying Gait Pathology after ACL Reconstruction Using Temporal Characteristics of Kinetics and Electromyography.Medicine and science in sports and exercise · 2022Article
- Innovative rehabilitative bracing with applied resistance improves walking pattern recovery in the early stages of rehabilitation after ACL reconstruction: a preliminary investigation.BMC musculoskeletal disorders · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
Early-onset knee osteoarthritis (OA) is associated with gait asymmetries after anterior cruciate ligament reconstruction (ACLR). Women have higher risks of sustaining non-contact injuries, and are more likely to present with aberrant movement patterns associated with the mechanism of injury (MOI). We hypothesized that sex and MOI would influence gait after ACLR. Seventy participants, grouped by sex and MOI, completed biomechanical testing during over-ground walking when they had full knee range of motion, trace or less knee effusion, greater than 80% quadriceps strength limb symmetry index, ability to hop on each leg without pain, and initiated running. Bilateral knee kinetics, kinematics, and joint contact forces were compared using mixed-model analysis of variance (α = .05). There was a three-way interaction effect of sex × MOI × limb for peak medial compartment contact force (P = .002), our primary outcome measure previously associated with OA development. Men with non-contact injuries walked with asymmetry characterized by underloading of the involved limb. Men with contact injuries walked with the most symmetrical loading. In women, no clear pattern emerged based on MOI. Targeting, and possibly prioritizing interventions for athletes who present with gait asymmetries after ACLR based on sex and MOI, may be necessary to optimize outcomes. Statement of Clinical Significance: Sex and MOI may influence walking mechanics, and could be considered in future interventions to target gait symmetry, as a response to interventions may vary based on differences in sex and MOI.
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Registered trials
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