Evidence map›Paper›PMID 32761898›Full record

SynthesisJournal of medical virology2021

A systematic review and meta-analysis of children with coronavirus disease 2019 (COVID-19).

Xiaojian Cui, Zhihu Zhao, Tongqiang Zhang, Wei Guo, Wenwei Guo, Jiafeng Zheng, Jiayi Zhang, Cuicui Dong, Ren Na, Lisheng Zheng and 9 more

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of medical virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06301802 (Urological Outcomes of Proactive Management of Children With Myelomeningocele), which is not on this map. Cited by 207 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
207citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06301802 unknown statusnot on this mapstarted 2024, after this paper: background citation

Urological Outcomes of Proactive Management of Children With Myelomeningocele

TypeobservationalSponsorAssiut UniversityRan2024 to 2026Enrolled40ConditionsUrologic DiseasesArmsCIC, Anticholinergic
3 · Its place in the literature

Who cites it

207 citing papers in PubMed, 11 syntheses or guidelines pooled it.

  1. Pooled it
  2. Neurological manifestations associated with SARS-CoV-2 infection in pediatric patients: a systematic review.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Trial
  13. Article
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

147 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Xiaojian CuiDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.ORCID 0000-0003-0204-7534
Zhihu ZhaoDepartment of Orthopaedic, Tianjin Hospital, Tianjin, PR China.
Tongqiang ZhangDepartment of Respiratory, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.ORCID 0000-0002-6945-1868
Wei GuoDepartment of Respiratory, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Wenwei GuoDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Jiafeng ZhengDepartment of Respiratory, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Jiayi ZhangDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Cuicui DongDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Ren NaDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Lisheng ZhengDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Wenliang LiDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Zihui LiuDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Jia MaDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Jinhu WangDepartment of Neonatal Surgery, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Sijia HeDepartment of National Center for Biodefense and Infectious Diseases, School of Systems Biology, George Mason University, Manassas, Virginia.ORCID 0000-0002-1932-1141
Yongsheng XuDepartment of Respiratory, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Ping SiDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Yongming ShenDepartment of Clinical Lab, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.
Chunquan CaiDepartment of Neurosurgery, Tianjin Children's Hospital (Children's Hospital of Tianjin University), Tianjin, PR China.

Funding

National Natural Science Foundation of China 81771589The Key Project of Tianjin Health Care Professionals 16KG166The Program of Tianjin Science and Technology Plan 18ZXDBSY00170
6 · The paper itself

Abstract

To provide a comprehensive and systematic analysis of demographic characteristics, clinical symptoms, laboratory findings, and imaging features of coronavirus disease 2019 (COVID-19) in pediatric patients. A meta-analysis was carried out to identify studies on COVID-19 from 25 December 2019 to 30 April 2020. A total of 48 studies with 5829 pediatric patients were included. Children of all ages were at risk for COVID-19. The main illness classification ranged as: 20% (95% confidence interval [CI]: 14%-26%; I

Indexed as

AdolescentChildChild, PreschoolCoughCOVID-19COVID-19 Nucleic Acid TestingCOVID-19 Serological TestingFemaleFeverHumansInfantInfant, NewbornMale2019-nCoVchildrencoronavirusCOVID-19meta-analysisSARS-CoV-2

Identifiers

PMID32761898
PMCPMC7436402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.