Trial reportCardiovascular drugs and therapy2021
Beneficial Effects of Baduanjin Exercise on Left Ventricular Remodelling in Patients after Acute Myocardial Infarction: an Exploratory Clinical Trial and Proteomic Analysis.
Trial report in Cardiovascular drugs and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05863767 (Effect of Baduanjin Sequential Therapy on Physical Functioning and Quality of Life Among Post CABG Patients.), which is not on this map. Cited by 13 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Baduanjin Sequential Therapy on Physical Functioning and Quality of Life Among Post CABG Patients.
Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- The Efficacy of Traditional Chinese Exercises in Patients With Chronic Heart Failure: An Umbrella Review and Meta-Analysis.Reviews in cardiovascular medicine · 2026Pooled it
- Evidence map of traditional Chinese exercises.Frontiers in public health · 2024Pooled it
- Exercise-based cardiac rehabilitation for coronary heart disease.The Cochrane database of systematic reviews · 2021Pooled it
- Rehabilitation of Cardiovascular Diseases in China.Journal of geriatric cardiology : JGC · 2024Article
- Effects of different traditional Chinese exercise in the treatment of essential hypertension: a systematic review and network meta-analysis.Frontiers in cardiovascular medicine · 2024Review
- Effects of traditional Chinese exercises on cardiac rehabilitation in patients with myocardial infarction: a meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2023Review
- From multi-omics approaches to personalized medicine in myocardial infarction.Frontiers in cardiovascular medicine · 2023Review
- Effects of Home-Based Baduanjin Exercise on Left Ventricular Remodeling in Patients With Acute Anterior ST-Segment Elevation Myocardial Infarction: Study Protocol for a Randomized Controlled Trial.Frontiers in cardiovascular medicine · 2022Article
- Exploring the therapeutic mechanism of Baduanjin in the treatment of elderly stable angina pectoris based on the gut microbiota-lipid metabolism spectrum: Study protocol for a randomized controlled trial.Frontiers in public health · 2022Article
- Effects of Baduanjin on glucose and lipid metabolism in diabetic patients: A protocol for systematic review and meta-analysis.Medicine · 2021Article
- The Safety of Baduanjin Exercise: A Systematic Review.Evidence-based complementary and alternative medicine : eCAM · 2021Review
- Quality indicators for cardiac rehabilitation after myocardial infarction in China: a consensus panel and practice test.BMJ open · 2020Article
- Movement-based mind-body interventions for cardiac rehabilitation: An updated systematic review of randomized controlled trials.Tzu chi medical journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe beneficial effects of physical exercise on cardiac remodelling improvement after myocardial infarction have already been suggested. However, the results of previous clinical trials have not been consistent. Moreover, the putative molecular mechanisms leading to the clinically observed effects of physical exercise still remain elusive.
aimWe aimed to evaluate whether the well-defined and strictly controlled traditional Chinese Qigong Baduanjin exercise (BE) would attenuate the adverse left ventricular (LV) remodelling in patients with ST-elevation myocardial infarction (STEMI).
methodsA total of 110 clinically stable STEMI patients, following successful revascularization of their infarcted coronary arteries, were randomized and enrolled in two groups: 56 were subjected to a 12-week BE-based cardiac rehabilitation programme (BE group), and the remaining 54 were exposed to the usual physical exercise (control group) for the same time period. The primary outcome was the change from baseline to 6 months in the echocardiographic LV end-diastolic volume index (ΔLVEDVi). Proteomic analysis was also performed to uncover associated mechanisms.
resultsCompared with the control group, the BE group showed significantly lower ΔLVEDVi (-5.1 ± 1.1 vs. 0.3 ± 1.2 mL/m
conclusionThis is the first study indicating that BE in STEMI patients can alleviate adverse LV remodelling associated with beneficial energy metabolism adaptation, inflammation curbing, and extracellular matrix organization adjustment.
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