Evidence map›Paper›PMID 32761396›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

Impact of COVID-19 on neurological manifestations: an overview of stroke presentation in pandemic.

Nida Fatima, Maher Saqqur, Fatima Qamar, Samia Shaukat, Ashfaq Shuaib

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. The relationship between COVID-19's severity and ischemic stroke: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. A review of ischemic stroke in COVID-19: currently known pathophysiological mechanisms.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Review
  8. Alzheimer's disease in elderly COVID-19 patients: potential mechanisms and preventive measures.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  9. Article
  10. Neurological manifestations of coronavirus disease 2019: exploring past to understand present.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Review
  11. Review
  12. Article
  13. Review
  14. Neurological manifestations of COVID-19 infection: an umbrella review.The Egyptian journal of neurology, psychiatry and neurosurgery · 2021
    Review
  15. Neurological manifestations and comorbidity associated with COVID-19: an overview.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Review
  16. Neurological reasons for consultation and hospitalization during the COVID-19 pandemic.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 5 institutions in 3 countries.

Nida FatimaDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. nfatima@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-0976-888X
Maher SaqqurDepartment of Neurology, University of Toronto Mississauga, Mississauga, Ontario, Canada.
Fatima QamarJohns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Samia ShaukatDepartment of Medicine, King Edward Medical University, Lahore, Pakistan.
Ashfaq ShuaibDepartment of Neurology, University of Alberta, Edmonton, Alberta, Canada.
Harvard University · USJohns Hopkins University · USKing Edward Medical University · PKUniversity of Alberta · CAUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corona virus disease 2019 (COVID-19) pandemic has become a globally challenging issue after its emergence in December 2019 from Wuhan, China. Despite its common presentation as respiratory distress, patients with COVID-19 have also shown neurological manifestation especially stroke. Therefore, the authors sought to determine the etiology, underlying risk factors, and outcomes among patients with COVID-19 presenting with stroke. We conducted a systematic review of the electronic database (PubMed, Google Scholar, Scopus, Medline, EMBASE, and Cochrane library) using different MeSH terms from November 2019 to June 2020. A total of 39 patients with stroke from 6 studies were included. The mean age of our included patients was 61.4 ± 14.2 years. Majority of the patients (n = 36, 92.3%) with COVID-19 had ischemic stroke, 5.1% (n = 2) had hemorrhagic stroke, and 2.6% (n = 1) had cerebral venous thrombosis at the time of initial clinical presentation. Almost all of the patients presented had underlying risk factors predisposing to stroke which included diabetes mellitus, hyperlipidemia, hypertension, and previous history of cerebrovascular disease. 51.2% (n = 20) of the included patients infected with COVID-19 with stroke died, while remaining patients were either discharged home or transferred to a rehabilitation unit. Exploring the neurological manifestation in terms of stroke among patients with COVID-19 is a step towards better understanding of the virus, preventing further spread, and treating the patients affected by this pandemic.

Indexed as

BetacoronavirusPandemicsBrain IschemiaCoronavirus InfectionsCOVID-19Diabetes MellitusHumansHypertensionNervous System DiseasesPneumonia, ViralRisk FactorsSARS-CoV-2StrokeCorona virusCOVID-19Neurological disordersPandemicStroke

Identifiers

PMID32761396
PMCPMC7406873
OpenAlexW3047382086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.