ArticleEuropean journal of nuclear medicine and molecular imaging2021
COVID-19 in the act: incidental 18F-FDG PET/CT findings in asymptomatic patients and those with symptoms not primarily correlated with COVID-19 during the United Kingdom coronavirus lockdown.
Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Contribution ofCurrent issues in molecular biology · 2025Review
- The value of FDG-PET/CT imaging in the assessment, monitoring, and management of COVID-19.European physical journal plus · 2023Review
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- Lymphopenia in patients affected by SARS-CoV-2 infection is caused by margination of lymphocytes in large bowel: an [European journal of nuclear medicine and molecular imaging · 2022Article
- A case-control evaluation of pulmonary and extrapulmonary findings of incidental asymptomatic COVID-19 infection on FDG PET-CT.The British journal of radiology · 2022Article
- Imaging of Hematological Patients in the Era of COVID-19.Acta haematologica · 2022Review
- Oncology and cardiology positron emission tomography/computed tomography faced with COVID-19: A review of available literature data.Frontiers in medicine · 2022Review
- FDG-PET/CT of COVID-19 and Other Lung Infections.Seminars in nuclear medicine · 2022Review
- FDG PET/CT imaging features and clinical utility in COVID-19.Clinical imaging · 2021Article
- Positron emission tomography in the COVID-19 pandemic era.European journal of nuclear medicine and molecular imaging · 2021Review
- Prevalence of interstitial pneumonia suggestive of COVID-19 atEuropean journal of nuclear medicine and molecular imaging · 2021Observational
- A comprehensive review of imaging findings in COVID-19 - status in early 2021.European journal of nuclear medicine and molecular imaging · 2021Review
- State of the art ofClinical and translational imaging · 2021Review
- Total-Body PET Imaging in Infectious Diseases.PET clinics · 2021Review
- Asymptomatic COVID-19 cancer patients incidentally discovered during F18-FDG PET/CT monitoring.Medicine and pharmacy reports · 2021Article
- Identify. Quantify. Predict. Why Immunologists Should Widely Use Molecular Imaging for Coronavirus Disease 2019.Frontiers in immunology · 2021Review
- Role of 2-[Pharmaceuticals (Basel, Switzerland) · 2020Review
- Incidental findings of COVID-19 in F18-FDG PET/CT from asymptomatic patients with cancer in two healthcare institutions in Bogotá, ColombiaBiomedica : revista del Instituto Nacional de Salud · 2020Article
- COVID-19-associated Parotid Gland Abscess.In vivo (Athens, Greece)Article
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe emergence of the novel SARS-CoV-2 pathogen and lethal COVID-19 disease pandemic poses major diagnostic challenges. The study aims to describe the spectrum and prevalence of thoracic and extrathoracic incidental findings in patients who have undergone 18F-FDG PET/CT during the first 3 weeks of the COVID-19 UK lockdown.
methodsThis is a single-centre retrospective controlled observational study. 18F-FDG PET/CT scans (n = 160) acquired from 23/3/2020 to 9/4/2020 were retrospectively reviewed for incidental findings in the lungs and extrapulmonary sites (heart, nasal sinuses, parotid and salivary glands, colon, large vessels, renal cortex, brain, spleen and testes). A date-matched control group (n = 205) of patients from 2019 was used for comparison.
resultsThe total prevalence of suspicious findings was 26/160 (16.25%). Fifteen patients presented with incidental findings in the lungs, while eleven patients had only non-pulmonary incidental findings. There was a significant increase in the appearance of incidental 18F-FDG PET/CT findings during the 2nd week (OR = 3.8) and 3rd week (OR = 7.6) in relation to the 1st week. There was a significant increase in the average maximum standardised uptake values (SUVmax) in the parotid/salivary glands of patients scanned during week 2 in relation to week 1 (p = 0.036). There was no significant difference in the prevalence of incidental findings compared to the control group, but the number of pulmonary vs. extrathoracic findings was different between the two populations.
conclusionThe study provides a novel base of evidence to identify asymptomatic patients and those without symptoms strongly associated with COVID-19 with incidental 18F-FDG PET/CT findings suspicious of SARS-CoV-2 infection during the initial stages of the pandemic.
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