Evidence map›Paper›PMID 32761196›Full record

ArticleSchizophrenia bulletin2021

Brief Psychotic Disorder During the National Lockdown in Italy: An Emerging Clinical Phenomenon of the COVID-19 Pandemic.

Armando D Agostino, Simone D'Angelo, Barbara Giordano, Anna Chiara Cigognini, Margherita Lorenza Chirico, Cristiana Redaelli, Orsola Gambini

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Schizophrenia bulletin, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Armando D AgostinoDepartment of Mental Health, San Paolo Hospital, ASST Santi Paolo e Carlo, Milan, Italy.
Simone D'AngeloDepartment of Health Sciences, Università degli Studi di Milano, Milan, Italy.
Barbara GiordanoDepartment of Health Sciences, Università degli Studi di Milano, Milan, Italy.
Anna Chiara CigogniniDepartment of Health Sciences, Università degli Studi di Milano, Milan, Italy.
Margherita Lorenza ChiricoDepartment of Mental Health, San Paolo Hospital, ASST Santi Paolo e Carlo, Milan, Italy.
Cristiana RedaelliDepartment of Mental Health, San Paolo Hospital, ASST Santi Paolo e Carlo, Milan, Italy.
Orsola GambiniDepartment of Mental Health, San Paolo Hospital, ASST Santi Paolo e Carlo, Milan, Italy.
University of Milan · ITOspedale San Paolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of the COVID-19 pandemic on psychosis remains to be established. Here we report 6 cases (3 male and 3 female) of first-episode psychosis (FEP) admitted to our hospital in the second month of national lockdown. All patients underwent routine laboratory tests and a standardized assessment of psychopathology. Hospitalization was required due to the severity of behavioral abnormalities in the context of a full-blown psychosis (the Brief Psychiatric Rating Scale [BPRS] = 75.8 ± 14.6). Blood tests, toxicological urine screening, and brain imaging were unremarkable, with the exception of a mild cortical atrophy in the eldest patient (male, 73 years). All patients were negative for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) throughout their stay, but 3 presented the somatic delusion of being infected. Of note, all 6 cases had religious/spiritual delusions and hallucinatory contents. Despite a generally advanced age (53.3 ± 15.6), all patients had a negative psychiatric history. Rapid discharge (length of stay = 13.8 ± 6.9) with remission of symptoms (BPRS = 27.5 ± 3.1) and satisfactory insight were possible after relatively low-dose antipsychotic treatment (Olanzapine-equivalents = 10.1 ± 5.1 mg). Brief psychotic disorder/acute and transient psychotic disorder diagnoses were confirmed during follow-up visits in all 6 cases. The youngest patient (female, 23 years) also satisfied the available criteria for brief limited intermittent psychotic symptoms. Although research on larger populations is necessary, our preliminary observation suggests that intense psychosocial stress associated with a novel, potentially fatal disease and national lockdown restrictions might be a trigger for FEP.

Indexed as

Communicable Disease ControlDelusionsHallucinationsPsychotic DisordersAdultAgedAntipsychotic AgentsCOVID-19FemaleFollow-Up StudiesHumansItalyMaleMiddle AgedRemission InductionStress, PsychologicalAntipsychotic Agentsacute and transient psychotic episodebouffée délirantebrief psychotic episodesCOVID-19reactive psychosisSARS-CoV-2

Identifiers

PMID32761196
PMCPMC7454891
OpenAlexW3048006989

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.