Evidence map›Paper›PMID 32761077›Full record

ArticleDatabase : the journal of biological databases and curation2020

FLUTE: Fast and reliable knowledge retrieval from biomedical literature.

Emilee Holtzapple, Cheryl A Telmer, Natasa Miskov-Zivanov

Abstract read
In one paragraph

Article in Database : the journal of biological databases and curation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  3. Automated model refinement using perturbation-observation pairs.NPJ systems biology and applications · 2025
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emilee HoltzappleDepartment of Computational and Systems Biology, University of Pittsburgh, 3501 Fifth Ave, Pittsburgh, Pennsylvania 15213, USA.
Cheryl A TelmerMolecular Biosensor and Imagining Center, Carnegie Mellon University, 4400 Fifth Ave, Pittsburgh, Pennsylvania 15213, USA.
Natasa Miskov-ZivanovDepartment of Computational and Systems Biology, University of Pittsburgh, 3501 Fifth Ave, Pittsburgh, Pennsylvania 15213, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

State-of-the-art machine reading methods extract, in hours, hundreds of thousands of events from the biomedical literature. However, many of the extracted biomolecular interactions are incorrect or not relevant for computational modeling of a system of interest. Therefore, rapid, automated methods are required to filter and select accurate and useful information. The FiLter for Understanding True Events (FLUTE) tool uses public protein interaction databases to filter interactions that have been extracted by machines from databases such as PubMed and score them for accuracy. Confidence in the interactions allows for rapid and accurate model assembly. As our results show, FLUTE can reliably determine the confidence in the biomolecular interactions extracted by fast machine readers and at the same time provide a speedup in interaction filtering by three orders of magnitude. Database URL: https://bitbucket.org/biodesignlab/flute.

Indexed as

Databases, ProteinProtein Interaction MapsComputational BiologyData MiningPublicationsPubMed

Identifiers

PMID32761077
PMCPMC7408180

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.