Evidence map›Paper›PMID 32761019›Full record

ArticleChemical communications (Cambridge, England)2020

Intracellular photoswitchable neuropharmacology driven by luminescence from upconverting nanoparticles.

Jun Zhao, Graham C R Ellis-Davies

Open access · greenAbstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jun ZhaoDepartment of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA. graham.davies@mssm.edu.ORCID http://orcid.org/0000-0003-3663-1595
Graham C R Ellis-DaviesDepartment of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA. graham.davies@mssm.edu.ORCID http://orcid.org/0000-0003-4179-5455
Icahn School of Medicine at Mount Sinai · US

Funding

PHOTOCHEMICAL REGULATION OF CALCIUM IN CELL PHYSIOLOGYR01GM053395 · NIGMS · OREGON HEALTH AND SCIENCE UNIVERSITY · PI ELLIS-DAVIES, GRAHAM · 1995 to 2020
$6.1M
Light-Driven Control of Neurons in Vitro and in VivoR35NS111600 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Graham Ellis-Davies · 2019 to 2026
$5.5M
NIGMS NIH HHS R01 GM053395NINDS NIH HHS R35 NS111600
6 · The paper itself

Abstract

Photoswitchable drugs are small-molecule optical probes that undergo chromatically selective control of drug efficacy using, most often, UV-visible light. Here we report that luminescence produced by near-infrared stimulation of NaYF4:TmYb nanoparticles can be used for "remote control" of an azobenzene-based photochromic ion channel blocker of neurons in living brain slices.

Indexed as

LightUltraviolet RaysAnimalsAzo CompoundsFluorescent DyesFluoridesIon ChannelsIsomerismMetal NanoparticlesMiceNeuronsTerbiumThuliumYttriumazobenzeneAzo CompoundsFluorescent DyesFluoridesIon Channelssodium yttriumtetrafluorideTerbiumThuliumYttrium

Identifiers

PMID32761019
PMCPMC7812838
OpenAlexW3046937507

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.