ReviewJournal of patient-centered research and reviews2020
HIV Preexposure Prophylaxis and Treatment as Prevention - Beliefs and Access Barriers in Men Who Have Sex With Men (MSM) and Transgender Women: A Systematic Review.
Review in Journal of patient-centered research and reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06159582 (eSTEP), which is not on this map. Cited by 47 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum
Who cites it
47 citing papers in PubMed, 79 citations in OpenAlex.
- Trial
- Health Care Providers' Reported Barriers to Pre-Exposure Prophylaxis Initiation Among Cisgender Women.Health education & behavior : the official publication of the Society for Public Health Education · 2026Article
- PrEP-Related Medical, Structural and Institutional Mistrust among a Socioeconomically Diverse Sample of Black, Latine, Asian, and White Young Sexual Minority Men: Lived Experiences of Intersectional Inequity.AIDS and behavior · 2026Article
- Barriers to and Facilitators of Heterosexual Men's Engagement with the PrEP Care Continuum in Sub-Saharan Africa: A Scoping Review.AIDS and behavior · 2026Article
- Developing the PATH-GP (Prevention and Testing for HIV in General Practice) intervention: a person-based approach intervention development study to increase HIV testing and PrEP access.The British journal of general practice : the journal of the Royal College of General Practitioners · 2026Article
- Toward an End to the HIV Epidemic for Black Women in the US South: Redefining the Success of Preexposure Prophylaxis Uptake for Black Women.Sexually transmitted diseases · 2025Article
- Barriers: The discursive problematization and transformation of HIV-prevention service provision in England (2016-2020).Social theory & health : STH · 2025Article
- The future of HIV: challenges in meeting the 2030 Ending the HIV Epidemic in the US (EHE) reduction goal.AIDS (London, England) · 2025Article
- Sexual behavior stigma among cisgender gay, bisexual, and other men who have sex with men in nine NHBS cities across the United States: Burden and associations with PrEP continuum and HIV care continuum outcomes.Stigma and health · 2025Article
- The Future of HIV: Challenges in meeting the 2030medRxiv : the preprint server for health sciences · 2025Article
- Article
- Blending De-implementation and Implementation to Promote Adoption of Universal PrEP Guidelines: Determinants, Strategies, and Outcomes.Critical public health · 2025Article
- Article
- Knowledge and Awareness of Pre-Exposure Prophylaxis Among Men in Sub-Saharan Africa: A Scoping Review Protocol.Health science reports · 2025Article
- Characterizing syndemic HIV risk profiles and mHealth intervention acceptability among patients in the emergency department.Psychology, health & medicine · 2025Article
- Measuring sexual behavior stigma among cisgender men who have sex with men: an assessment of cross-country measurement invariance.Stigma and health · 2024Article
- Are Rights-Based Services Important? An Adolescent PrEP Demonstration Project in Brazil.Health and human rights · 2024Article
- Variations in HIV Prevention Coverage in Subpopulations of Australian Gay and Bisexual Men, 2017-2021: Implications for Reducing Inequities in the Combination Prevention Era.AIDS and behavior · 2024Article
- Social, Structural, Behavioral, and Clinical Barriers Influencing Pre-exposure Prophylaxis (PrEP) Use Among Young Black Men Who Have Sex with Men in the South: A Qualitative Update to a 2016 Study.Archives of sexual behavior · 2024Article
- Informing Acceptability and Feasibility of Digital Phenotyping for Personalized HIV Prevention among Marginalized Populations Presenting to the Emergency Department.Proceedings of the ... Annual Hawaii International Conference on System Sciences. Annual Hawaii International Conference on System Sciences · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWhile the annual rate of new HIV infections and diagnoses has remained stable for most groups, troubling increases are seen in transgender women and racial/ethnic-minority men who have sex with men (MSM), groups that are disproportionately affected by HIV. The primary purpose of this systematic review is to examine factors that impact attitudes and beliefs about preexposure prophylaxis (PrEP) and treatment as prevention (TasP) and to explore barriers to PrEP uptake in MSM and transgender women.
methodsUsing MeSH terms and relevant keywords, we conducted a systematic review of studies published between 2010 and 2019. We searched 4 literature databases and identified studies on MSM and transgender women to elucidate perceptions of PrEP and TasP as well as barriers to access.
resultsThe search yielded several prominent themes associated with beliefs about HIV prevention approaches and barriers to PrEP access in MSM and transgender women. One was a lack of awareness or insufficient knowledge of PrEP and TasP. Structural barriers and geographic isolation also prevent access to HIV prevention. Sexual minority and HIV-related stigma, internalized homonegativity, and misinterpretations of messages within HIV prevention campaigns have negatively impacted PrEP uptake and beliefs about PrEP and TasP. Quality of the relationship MSM or transgender people have with their health care provider can facilitate or hinder HIV prevention. Finally, variability in beliefs about the efficacy of TasP has negatively affected the impact of TasP messaging campaigns.
conclusionsAlthough there is evidence of increasing PrEP use in at-risk individuals, several barriers prevent wider acceptance and uptake. Misunderstanding about the meaning of "undetectable" and skepticism about the evidence behind TasP messaging campaigns are likely to delay the World Health Organization's stated goal of getting to zero transmissions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.