Evidence map›Paper›PMID 32760738›Full record

ReviewFrontiers in molecular biosciences2020

Current State of Target Treatment in BRAF Mutated Melanoma.

Enrica Teresa Tanda, Irene Vanni, Andrea Boutros, Virginia Andreotti, William Bruno, Paola Ghiorzo, Francesco Spagnolo

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Non-coding RNA profiling in BRAFScientific data · 2025
    Article
  7. Combined Targeting of PD-1 and TIM-3 in Patients with Locally Advanced or Metastatic Melanoma: AMBER Cohorts 1c, 1e, and 2A.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025
    Article
  8. Article
  9. Current Treatment Paradigms for Advanced Melanoma with Brain Metastases.International journal of molecular sciences · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Enrica Teresa TandaMedical Oncology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Irene VanniGenetics of Rare Cancers, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Andrea BoutrosMedical Oncology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Virginia AndreottiGenetics of Rare Cancers, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
William BrunoGenetics of Rare Cancers, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Paola GhiorzoGenetics of Rare Cancers, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.
Francesco SpagnoloMedical Oncology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Incidence of melanoma has been constantly growing during the last decades. Although most of the new diagnoses are represented by thin melanomas, the number of melanoma-related deaths in 2018 was 60,712 worldwide (Global Cancer Observatory, 2019). Until 2011, no systemic therapy showed to improve survival in patients with advanced or metastatic melanoma. At that time, standard of care was chemotherapy, with very limited results. The identification of

Indexed as

BRAF mutationMAPK pathwaymelanomametastatic diseasetargeted therapy

Identifiers

PMID32760738
PMCPMC7371970

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.