Evidence map›Paper›PMID 32760734›Full record

ReviewFrontiers in nutrition2020

Diet and Transgenerational Epigenetic Inheritance of Breast Cancer: The Role of the Paternal Germline.

Raquel Santana da Cruz, Elaine Chen, Megan Smith, Jaedus Bates, Sonia de Assis

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Father's occupation and colorectal cancer in his adult offspring.Journal of the National Cancer Institute · 2025
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  12. Diagnostic Value of FTO Combined with CEA or CYFRA21-1 in Nonsmall Cell Lung Cancer.Evidence-based complementary and alternative medicine : eCAM · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Raquel Santana da CruzDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States.
Elaine ChenDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States.
Megan SmithDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States.
Jaedus BatesDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States.
Sonia de AssisDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, United States.
Georgetown University Medical Center · USGeorgetown University · US

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI MARCUS S NOEL · 1990 to 2026
$71.5M
Maternal Morbidity and Mortality: Risk Factors, Early Detection and Personalized InterventionUL1TR001409 · NCATS · GEORGETOWN UNIVERSITY · PI GONDRE-LEWIS, MARJORIE C, MELLMAN, THOMAS A · 2015 to 2024
$37.8M
Parental Exposure to High Fats Diets and Risk of Pancreatic Cancer in the OffspriK22CA178309 · NCI · GEORGETOWN UNIVERSITY · PI DE ASSIS, SONIA · 2015 to 2017
$459k
NCATS NIH HHS UL1 TR001409NCI NIH HHS K22 CA178309NCI NIH HHS P30 CA051008
6 · The paper itself

Abstract

The past decade has made evident that in addition to passing their genetic material at conception, parents also transmit a molecular memory of past environmental experiences, including nutritional status, to their progeny through epigenetic mechanisms. In the 1990s, it was proposed that breast cancer originates

Indexed as

breast cancerdietepigenetic inheritancepaternal germlinetransgenerational effects

Identifiers

PMID32760734
PMCPMC7373741
OpenAlexW3042757113

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.