Evidence map›Paper›PMID 32760733›Full record

ArticleFrontiers in medicine2020

Multisystem Inflammatory Syndrome With Complete Kawasaki Disease Features Associated With SARS-CoV-2 Infection in a Young Adult. A Case Report.

Elie Cogan, Pierre Foulon, Olivier Cappeliez, Nicole Dolle, Gaëlle Vanfraechem, Daniel De Backer

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 6 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 6 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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  4. COVID-19 and the Heart: A Systematic Review of Cardiac Autopsies.Frontiers in cardiovascular medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Elie CoganDepartment of Internal Medicine, CHIREC Hospital, Brussels, Belgium.
Pierre FoulonDepartment of Intensive Care, CHIREC Hospital, Brussels, Belgium.
Olivier CappeliezDepartment of Radiology, CHIREC Hospital, Brussels, Belgium.
Nicole DolleDepartment of Biochemistry, CHIREC Hospital, Brussels, Belgium.
Gaëlle VanfraechemDepartment of Infectious Diseases, CHIREC Hospital, Brussels, Belgium.
Daniel De BackerUniversité Libre de Bruxelles (ULB), Brussels, Belgium.
Centre Hospitalier Interrégional Edith Cavell · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A severe multisystem inflammatory syndrome associated with Kawasaki disease manifestations (MIS-C) has been recently reported in children with signs of recent infection with SARS-CoV-2. We here reported the case of a young adult woman who presented the complete manifestations of Kawasaki disease associated with a severe myocarditis, acute respiratory distress syndrome and hemodynamic instability a few weeks after a transient anosmia. The detection of specific antibodies to SARS-CoV-2 in the absence of detection of the virus suggested that the syndrome was the result of a delayed immune response to a recent COVID-19 infection. A combined treatment with colchicine, tocilizumab, high dose immunoglobulins, and methylprednisolone allowed to control the inflammatory process and to limit the development of coronary aneurysm. The patient recovered without sequelae. This case emphasized the importance of SARS-CoV-2 serology for the diagnosis of delayed immune complications of COVID-19. Clinicians caring for adult patients must be aware that not only children but also young adults can be affected by a multisystem inflammatory syndrome with KD features associated with COVID-19.

Indexed as

case reportCOVID-19Kawasaki diseaseMIS-CSARS-CoV-2serologytocilizumab

Identifiers

PMID32760733
PMCPMC7371855
OpenAlexW3042875257

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.