ArticleFrontiers in chemistry2020
Design and Synthesis of Chitosan-Gelatin Hybrid Hydrogels for 3D Printable
Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Spiro-Ometad As A Promising Substrate In Biomedical Devices.ChemistryOpen · 2025Article
- Review
- All-Cellulose Hydrogel-Based Bioinks for the Versatile 3D Bioprinting of Different Cell Lines.Biomacromolecules · 2025Article
- Prospects and Challenges of Chitosan-Based Drug Carriers for Anticancer Agents' Delivery Against Lung Cancer: A Review.Drug design, development and therapy · 2025Review
- Click Chemistry for Biofunctional Polymers: From Observing to Steering Cell Behavior.Chemical reviews · 2024Review
- Recent Advancements in Hydrogel Biomedical Research in Italy.Gels (Basel, Switzerland) · 2024Review
- Chitosan and Its Derivatives: Preparation and Antibacterial Properties.Materials (Basel, Switzerland) · 2023Review
- Prospects of Using Chitosan-Based Biopolymers in the Treatment of Peripheral Nerve Injuries.International journal of molecular sciences · 2023Review
- Chitosan-Based Hydrogel in the Management of Dermal Infections: A Review.Gels (Basel, Switzerland) · 2023Review
- Advances in Gelatin Bioinks to Optimize Bioprinted Cell Functions.Advanced healthcare materials · 2023Review
- Characterization of a Bioink Combining Extracellular Matrix-like Hydrogel with Osteosarcoma Cells: Preliminary Results.Gels (Basel, Switzerland) · 2023Article
- Gelatin and Bioactive Glass Composites for Tissue Engineering: A Review.Journal of functional biomaterials · 2022Review
- Silver Nanoparticles andInternational journal of molecular sciences · 2022Article
- Development of Chitosan/Gelatin-Based Hydrogels Incorporated with Albumin Particles.International journal of molecular sciences · 2022Article
- Current Trends in Biomedical Hydrogels: From Traditional Crosslinking to Plasma-Assisted Synthesis.Polymers · 2022Review
- Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics.Cancers · 2022Article
- A Guide to Polysaccharide-Based Hydrogel Bioinks for 3D Bioprinting Applications.International journal of molecular sciences · 2022Review
- Polymeric Hydrogels for Controlled Drug Delivery to Treat Arthritis.Pharmaceutics · 2022Review
- Topical Chitosan-Based Thermo-Responsive Scaffold Provides Dexketoprofen Trometamol Controlled Release for 24 h Use.Pharmaceutics · 2021Article
- Combined Analytical Approaches to Standardize and Characterize Biomaterials Formulations: Application to Chitosan-Gelatin Cross-Linked Hydrogels.Biomolecules · 2021Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of 3D printable hydrogels based on the crosslinking between chitosan and gelatin is proposed. Chitosan and gelatin were both functionalized with methyl furan groups. Chemical modification was performed by reductive amination with methyl furfural involving the lysine residues of gelatin and the amino groups of chitosan to generate hydrogels with tailored properties. The methyl furan residues present in both polymers were exploited for efficient crosslinking via Diels-Alder ligation with PEG-Star-maleimide under cell-compatible conditions. The obtained chitosan-gelatin hybrid was employed to formulate hydrogels and 3D printable biopolymers and its processability and biocompatibility were preliminarily investigated.
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