Evidence map›Paper›PMID 32760648›Full record

ArticleLeukemia research reports2020

Near tetrapoloid karyotype with translocation t(11;14) in a Moroccan patient with amyloid light-chain amyloidosis and multiple myeloma.

Hasna Hamdaoui, Abdelhafid Natiq, Oumaima Benlarroubia, Thomas Liehr, Hind Dehbi, Latifa Loukhmas, Fatima Chegdani

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PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Hasna HamdaouiNational Reference Laboratory, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
Abdelhafid NatiqDépartement de génétique médicale, Institut national d'hygiène, Rabat, Morocco.
Oumaima BenlarroubiaNational Reference Laboratory, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.
Thomas LiehrDepartment of Medical Genetics, University of Jena, Institute for Humangenetics, D-07740 Jena, Germany.
Hind DehbiLaboratory of Cellular and Molecular Pathology, Faculty of Medicine and Pharmacy of Casablanca, University Hassan II, Casablanca, Morocco.
Latifa LoukhmasCheikh Khalifa International Hospital, Casablanca, Morocco.
Fatima ChegdaniUniversity Hassan II Casablanca, Faculty of sciences Ain Chock Casablanca, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytogenetic and iFISH plays a major part in the diagnosis of the MM and have an important prognostic significance. 10-15% of patients with amyloidosis will also have multiple myeloma (MM). Few studies have addressed the clinical and cytogenetic features of patients with AL amyloidosis with concurrent multiple myeloma. This study of MM case in which we found a near tetraploid complex karyotype with the t(11;14) (q13;q32) abnormality in cytogenetic analysis and the presence of t(4;14) and del(17p) by iFISH, referred to several studies which showed the translocation t(11;14) as the most frequent abnormality in both AL amyloidosis and MM.

Indexed as

AL amyloidosiscytogenetic analysisdel 17pFISHIGH/FGFR3Multiple myeloma

Identifiers

PMID32760648
PMCPMC7390876

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