Evidence map›Paper›PMID 32760576›Full record

ArticleF1000Research2019

Development of an informatics system for accelerating biomedical research.

Vivek Navale, Michele Ji, Olga Vovk, Leonie Misquitta, Tsega Gebremichael, Alison Garcia, Yang Fann, Matthew McAuliffe

Abstract read
In one paragraph

Article in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Genetic testing for inherited eye conditions in over 6,000 individuals through the eyeGENE network.American journal of medical genetics. Part C, Seminars in medical genetics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vivek NavaleOffice of Intramural Research, Center for Information Technology, National Institutes of Health, USA, Bethesda, Maryland, 20892, USA.ORCID 0000-0002-7110-8946
Michele JiOffice of Intramural Research, Center for Information Technology, National Institutes of Health, USA, Bethesda, Maryland, 20892, USA.
Olga VovkGeneral Dynamics Information Technology, Inc., Fairfax, Virginia, 22030, USA.
Leonie MisquittaSapient Government Services, Arlington, Virginia, 22201, USA.
Tsega GebremichaelSapient Government Services, Arlington, Virginia, 22201, USA.
Alison GarciaSapient Government Services, Arlington, Virginia, 22201, USA.
Yang FannIntramural IT and Bioinformatics Program, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, 20892, USA.
Matthew McAuliffeOffice of Intramural Research, Center for Information Technology, National Institutes of Health, USA, Bethesda, Maryland, 20892, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Biomedical Research Informatics Computing System (BRICS) was developed to support multiple disease-focused research programs. Seven service modules are integrated together to provide a collaborative and extensible web-based environment. The modules-Data Dictionary, Account Management, Query Tool, Protocol and Form Research Management System, Meta Study, Data Repository and Globally Unique Identifier -facilitate the management of research protocols, to submit, process, curate, access and store clinical, imaging, and derived genomics data within the associated data repositories. Multiple instances of BRICS are deployed to support various biomedical research communities focused on accelerating discoveries for rare diseases, Traumatic Brain Injury, Parkinson's Disease, inherited eye diseases and symptom science research. No Personally Identifiable Information is stored within the data repositories. Digital Object Identifiers are associated with the research studies. Reusability of biomedical data is enhanced by Common Data Elements (CDEs) which enable systematic collection, analysis and sharing of data. The use of CDEs with a service-oriented informatics architecture enabled the development of disease-specific repositories that support hypothesis-based biomedical research.

Indexed as

Biomedical ResearchComputational BiologyBrain Injuries, TraumaticEye Diseases, HereditaryGenomicsHumansParkinson DiseaseRare DiseasesBiomedical repositoryFAIRInformatics systemTranslational Research

Identifiers

PMID32760576
PMCPMC7376384

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.