Evidence map›Paper›PMID 32760428›Full record

ArticleFrontiers in genetics2020

Identification of Novel Alleles and Structural Haplotypes of Major Histocompatibility Complex Class I and DRB Genes in Domestic Cat (

Masaharu Okano, Jiro Miyamae, Shingo Suzuki, Kohei Nishiya, Fumihiko Katakura, Jerzy K Kulski, Tadaaki Moritomo, Takashi Shiina

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Masaharu OkanoDepartment of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Jiro MiyamaeFaculty of Veterinary Medicine, Okayama University of Science, Imabari, Japan.
Shingo SuzukiDivision of Basic Medical Science and Molecular Medicine, Department of Molecular Life Science, Tokai University, Isehara, Japan.
Kohei NishiyaDepartment of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Fumihiko KatakuraDepartment of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Jerzy K KulskiDivision of Basic Medical Science and Molecular Medicine, Department of Molecular Life Science, Tokai University, Isehara, Japan.
Tadaaki MoritomoDepartment of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Fujisawa, Japan.
Takashi ShiinaDivision of Basic Medical Science and Molecular Medicine, Department of Molecular Life Science, Tokai University, Isehara, Japan.
Nihon University · JPTokai University · JPOkayama University of Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The major histocompatibility complex (MHC) is a highly polymorphic and duplicated genomic region that encodes transplantation and immune regulatory molecules. Although it is well-known that particular MHC allelic polymorphisms and haplotypes are genetically relate to immune-mediated diseases detailed information of the cat MHC (Feline Leukocyte Antigen; FLA) genetic and haplotypic structure and diversity is limited in comparison to humans and many other species. In this study, to better understand the degree and types of allele and allelic haplotype diversity of FLA-class I (FLA-I) and FLA-DRB loci in domestic cats, we identified six expressible FLA-I loci in peripheral white blood cells by

Indexed as

domestic cathaplotypemajor histocompatibility complex (MHC)next generation sequencing (NGS)polymorphism

Identifiers

PMID32760428
PMCPMC7375346
OpenAlexW3042880940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.