ReviewFrontiers in physiology2020
Sarcoplasmic Hypertrophy in Skeletal Muscle: A Scientific "Unicorn" or Resistance Training Adaptation?
Review in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 63 citations in OpenAlex.
- Analytical approaches to account for muscle size when evaluating strength.European journal of applied physiology · 2026Review
- Actinidin-Enriched Kiwifruit Concentrate (Kwd+International journal of molecular sciences · 2026Article
- A novel pulley-vest model enables progressive resistance exercise in rats without tail loading.Journal of muscle research and cell motility · 2026Article
- Differential motor unit firing rate and hypertrophic adaptations of the vastus lateralis despite similar strength increases following high-load versus combined high- and low-load resistance training interventions.Experimental brain research · 2026Article
- Review
- A study on the effect of 12-week unstable bench press barbell training on improving upper limb muscle strength of college students.Frontiers in physiology · 2026Article
- The influence of high-load and combined high- and low-load resistance training on electromyographic behavior during an absolute muscular endurance task.European journal of applied physiology · 2025Article
- Load-induced human skeletal muscle hypertrophy: Mechanisms, myths, and misconceptions.Journal of sport and health science · 2025Review
- Physiological and Physical Determinants of Flat-Water Kayaking.Muscles (Basel, Switzerland) · 2025Review
- Part I: Development and Implementation of the Ten, Five, Three (TFT) Model for Resistance Training.Muscles (Basel, Switzerland) · 2025Review
- The Influence of Step Load Periodisation Based on Time Under Tension in Hypoxic Conditions on Hormone Concentrations and Postoperative ACL Rehabilitation of a Judo Athlete: A Case Study.Journal of clinical medicine · 2025Article
- Effects of chronic low-frequency pulsed magnetic fields exposure on the contractility and morphology of biceps brachii in healthy adults-a randomized controlled, double-blind trial.Frontiers in medicine · 2025Article
- Optimizing Resistance Training for Sprint and Endurance Athletes: Balancing Positive and Negative Adaptations.Sports medicine (Auckland, N.Z.) · 2024Review
- Article
- Effects of low-load resistance training with blood flow restriction on muscle fiber myofibrillar and extracellular area.Frontiers in physiology · 2024Article
- Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions.Physiological reviews · 2023Review
- The molecular athlete: exercise physiology from mechanisms to medals.Physiological reviews · 2023Review
- Resistance exercise: a mighty tool that adapts, destroys, rebuilds and modulates the molecular and structural environment of skeletal muscle.Physical activity and nutrition · 2023Article
- Molecular predictors of resistance training outcomes in young untrained female adults.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Metabolic reprogramming underlies cavefish muscular endurance despite loss of muscle mass and contractility.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skeletal muscle fibers are multinucleated cells that contain mostly myofibrils suspended in an aqueous media termed the sarcoplasm. Select evidence suggests sarcoplasmic hypertrophy, or a disproportionate expansion of the sarcoplasm relative to myofibril protein accretion, coincides with muscle fiber or tissue growth during resistance training. There is also evidence to support other modes of hypertrophy occur during periods of resistance training including a proportional accretion of myofibril protein with fiber or tissue growth (i.e., conventional hypertrophy), or myofibril protein accretion preceding fiber or tissue growth (i.e., myofibril packing). In this review, we discuss methods that have been used to investigate these modes of hypertrophy. Particular attention is given to sarcoplasmic hypertrophy throughout. Thus, descriptions depicting this process as well as the broader implications of this phenomenon will be posited. Finally, we propose future human and rodent research that can further our understanding in this area of muscle physiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.