Evidence map›Paper›PMID 32760265›Full record

ArticleFrontiers in neuroinformatics2019

Deep Learning Deformation Initialization for Rapid Groupwise Registration of Inhomogeneous Image Populations.

Sahar Ahmad, Jingfan Fan, Pei Dong, Xiaohuan Cao, Pew-Thian Yap, Dinggang Shen

Abstract read
In one paragraph

Article in Frontiers in neuroinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Groupwise Image Alignment via Self Quotient Images.Sensors (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sahar AhmadDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, United States.
Jingfan FanDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, United States.
Pei DongDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, United States.
Xiaohuan CaoDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, United States.
Pew-Thian YapDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, United States.
Dinggang ShenDepartment of Radiology and BRIC, University of North Carolina, Chapel Hill, NC, United States.

Funding

Longitudinal Mapping of Human Brain Development in the First Years of LifeR01EB008374 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2009 to 2024
$5.1M
Development of Robust Brain Measurement Tools Informed by Ultrahigh Field 7T MRIR01EB006733 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2008 to 2020
$4.5M
Analyzing Large-Scale Neuroimaging Data in Alzheimer's DiseaseRF1AG053867 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2016
$2.5M
Infant Brain Measurement and Super-Resolution Atlas ConstructionR01MH100217 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SHEN, DINGGANG · 2013 to 2016
$2.3M
NIA NIH HHS RF1 AG053867NIBIB NIH HHS R01 EB006733NIBIB NIH HHS R01 EB008374NIMH NIH HHS R01 MH100217
6 · The paper itself

Abstract

Groupwise image registration tackles biases that can potentially arise from inappropriate template selection. It typically involves simultaneous registration of a cohort of images to a common space that is not specified a priori. Existing groupwise registration methods are computationally complex and are only effective for image populations without large anatomical variations. In this paper, we propose a deep learning framework to rapidly estimate large deformations between images to significantly reduce structural variability. Specifically, we employ a multi-level graph coarsening method to agglomerate similar images into clusters, each represented by an exemplar image. We then use a deep learning framework to predict the initial deformations between images. Warping with the estimated deformations brings the images closer in the image manifold and their alignment can be further refined using conventional groupwise registration algorithms. We evaluated the effectiveness of our method in groupwise registration of MR brain images and compared it against state-of-the-art groupwise registration methods. Experimental results indicate that deformation initialization enables groupwise registration to converge significantly faster with competitive accuracy, therefore facilitates large-scale imaging studies.

Indexed as

brain templatesconvolutional neural networkdeep learninggraph coarseninggroupwise registrationMRI

Identifiers

PMID32760265
PMCPMC7373822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.