Evidence map›Paper›PMID 32760220›Full record

ReviewCancer cell international2020

Reshaping the role of m6A modification in cancer transcriptome: a review.

Guanqun Yang, Zhigang Sun, Nan Zhang

Open access · goldAbstract readReview
In one paragraph

Review in Cancer cell international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 51 citations in OpenAlex.

  1. TheGenes · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Switching from messenger RNAs to noncoding RNAs,World journal of gastrointestinal oncology · 2025
    Review
  6. Article
  7. Epitranscriptomic RNA mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  8. Article
  9. Article
  10. Role of NOncology reports · 2024
    Review
  11. RNA m6A methylation regulators in liver cancer.Cancer cell international · 2024
    Review
  12. The essential roles of mGenes & diseases · 2024
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. METTL3-Mediated LncRNAInternational journal of molecular sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Guanqun YangDepartment of Oncology, Jinan Central Hospital Affiliated to Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250013 Shandong China.
Zhigang SunDepartment of Thoracic Surgery, Jinan Central Hospital Affiliated to Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250013 Shandong China.
Nan ZhangDepartment of Oncology, Jinan Central Hospital Affiliated to Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, 250013 Shandong China.ORCID 0000-0002-6744-2810
Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N6-methyl-adenosine(m6A) modification emerges as an abundant and dynamic regulation throughout the Eukaryotic transcriptome. Dysregulation of the m6A regulators has increasingly been found in many neoplasms. It is reasonable to believe that m6A changes the fate of cancer cells and subsequently affected all aspects of cancer progression. In view of the context-dependent role of m6A modification, we emphasize a dual effect of m6A in a particular tumor model, that is, m6A plays a promoting role or a suppressing role in different stages of cancer. This novel sight is compared to the older view that a particular m6A regulator acts as a consistent role in cancer progression.

Indexed as

Cancerm6APosttranscriptional regulationRNA modificationTranscriptome

Identifiers

PMID32760220
PMCPMC7391667
OpenAlexW3045914854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.