Evidence map›Paper›PMID 32760196›Full record

ArticleInternational journal of biological sciences2020

LncRNA IGFBP4-1 promotes tumor development by activating Janus kinase-signal transducer and activator of transcription pathway in bladder urothelial carcinoma.

Chunjing Li, Yu Cao, Li Zhang, Jierong Li, Huayan Wu, Fengsheng Ling, Jintao Zheng, Jianfeng Wang, Bowei Li, Jun He and 12 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in International journal of biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Unveiling the functions of five recently characterized lncRNAs in cancer progression.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  2. Article
  3. Heliyon · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 1 country.

Chunjing LiDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Yu CaoNingxiang People's Hospital, The Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Ningxiang, China.
Li ZhangDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Jierong LiDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Huayan WuDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Fengsheng LingDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Jintao ZhengDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Jianfeng WangDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Bowei LiDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Jun HeDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Xumin XieDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Zhilin LiDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Yiping ChenDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Xuemei HeDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Mingjuan GuoDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Huiling WeiDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Jing YeDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Yun GuoDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Shilin ZhangDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Liang LiuNingxiang People's Hospital, The Affiliated Hospital of Hunan University of Traditional Chinese Medicine, Ningxiang, China.
Guoqing LiuDepartment of Urology, Affiliated Foshan Maternal and Child Healthcare Hospital, Southern Medical University, Foshan, China.
Chunxiao LiuDepartment of Urology, Zhujiang Hospital of Southern Medical University, Guangzhou, China.
Southern Medical University · CNFoshan Maternity and Child Health Care Hospital · CNZhujiang Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin-like growth factor binding protein 4-1 (IGFBP4-1), a new long noncoding RNA (lncRNA), has been reported to contribute to tumorigenesis and has been suggested to be a poor prognostic marker in human lung cancer. However, there still lacks basic studies that investigated the biological role of IGFBP4-1 in bladder urothelial carcinoma to date. In this study, we investigated the relationship between IGFBP4-1 expression and prognosis in patients with bladder cancer. Cell proliferation, cell cycle and cell apoptosis assays were performed to assess IGFBP4-1 function by up-regulating or down-regulating IGFBP4-1 in bladder cancer cells. A xenograft mice model was used to validate the

Indexed as

AnimalsApoptosisCarcinomaCell CycleCell Line, TumorCell ProliferationDatabases, GeneticDown-RegulationFemaleGene Expression Regulation, NeoplasticHumansInsulin-Like Growth Factor Binding Protein 4Janus KinasesMaleMiceMice, NudeIGFBP4 protein, humanInsulin-Like Growth Factor Binding Protein 4Janus KinasesRNA, Long NoncodingSTAT Transcription Factorsbladder cancerIGFBP4-1JAK/STATprognosisproliferation

Identifiers

PMID32760196
PMCPMC7378649
OpenAlexW3034676819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.